Brain Cellular Structure Flashcards
Subventricular Zone
produces new neurons for the olfactory bulb throughout life
neuronal progenitor cells produced here migrate to olfactory bulb where they differentiate into mature neurons
Hippocampus
part of the limbic system involved in learning and memory, especially spatial memory and transfer of short-term memory to long-term memory
Dentate Gyrus (Hippocampus)
produces new neurons throughout life and the new neurons are thought to be involved in establishing learning and memory
Excitatory Neurons
neurons that stimulate excitation in their target neurons
Inhibitory Neurons
Neurons that evoke inhibition in their targets
Modulatory
Neurons that evoke more complex effects on their target neurons
Astrocytes
glia that can communicate with neurons and modify the signals they send and receive
- release gliotransmitters (can’t trigger APs on their own)
- transfer oxygen, nutrients and other factors from the blood to neurons
Neurotransmitter recycling
excitatory Glu release by pre-synaptic neuron –> uptake/clearing of glu into astrocyte –> conversion of glu to gln inside astrocyte –> transfer of gln from astrocyte to neuron –> neurons then use gln as precursor to synthesise glu for storage
Astrocyte Functions
recycling neurotransmitters provide metabolic intermediates and survival factors phagocytosis of dead cells synaptic remodeling blood brain barrier protection neuron modulation
Oligodendrocytes
produce myelin
Saltatory Conduction
the jumping from one node of ranvier to the next of electrical signals –> speeds nerve propagation up
Microglia
- have immune cell functions in brain
- synaptic pruning
- neuron modulation