Memories and Processing Flashcards
cingulate gyrus
emotional value via cingulum
septal nuclei (ACh)
reward/incentive via fornix
amygdala
emotional content via the ventral amygdalofugal pathway
Korsakoff’s Psychosis
mammillary body degeneration
B1 deficiency + EtOH toxicity
can’t make new declarative memories so they make them up = “anamnestic confabulatory syndrome”
patients have intact intelligence
spatial memory is stored where?
posterior hippocampus
DLPFC (dorsolateral prefrontal cortex) lesions impair what type of memory?
working memory
what structures are used for short-term declarative memory?
medial temporal lobe diencephalic memory (Papez circuit)
what structures are used for long-term declarative memory in cortical storage?
circuit between ASSOCIATION CX. and PREFRONTAL CX. enables recall
does NOT require Papez recycling
what structures are used for working memory?
DLPFC = dorsolateral prefrontal cortex
bypasses the medial temporal lobe
what is medazolam (Versed) used for?
induce medial amnesia before surgery
benzodiazepine
what events can cause retrograde memory loss?
global hypoxia –> cortical loss
head trauma –> cortical damage
electroconvulsive therapy –> cortical damage
damage to what area can cause anterograde memory loss? What could cause this damage?
typically lesion affects HIPPOCAMPUS
Alzheimer’s
bilateral PCA infarct
viral infections (e.g. herpes simplex encephalitis)
focal ischemia
what helps lay down declarative memories and spatial memories?
hippocampi
