Eye Anatomy and Physiology (Sos; 3-26-24) Flashcards

1
Q

what is low myopia

A

-3 diopters or less

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2
Q

what is medium myopia

A

-3 to -6 diopters

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3
Q

what is high myopia?

A

-6 or more

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4
Q

Patient has high myopia, possible diagnoses?

A

glaucoma

retinal detachment

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5
Q

what are causes of diplopia?

A

Cataracts
Muscles: MG, Grave’s
Nerve: MS, DM, Gullian-Barre
Brain: stroke, tumor, aneurysm

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6
Q

fovea centralis is…

A

specialized region of macula lutea

200x increase in # of cone photoreceptors

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7
Q

foveola is…

A

no rods or BVs –> reduces light scatter –> highest visual acuity

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8
Q

what is the MC intraocular malignant neoplasm in adults?

A

uveal melanomas

incidence increases w/ age

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9
Q

where does retinal detachment happen? What can cause this?

A

between photo-receptors + retinal pigment epithelium.

  • trauma
  • hypertension
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10
Q

diabetic retinopathy causes

A
  • microangiopathy = thick BM
  • microhemorrhages
  • edema
  • hypoxia
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11
Q

what’s the most common cause of blindness in this country?

A

Age-Related Macular Degeneration (ARMD)

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12
Q

what happens in ARMD?

A

Neovascularization between the INNER CHOROID LAYER and BRUCH’S MEMBRANE (BM of retinal pigmented layer)

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13
Q

Tay-Sachs Disease causes what occular finding?

A

gangliosides accumulate in the ganglion cells in the retina
cherry red spot = only normal part of the retina
shows up in contrast to the retina

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14
Q

what is the MC primary intraocular malignant tumor in children? What is its cellular origin?

A

Retinoblastoma

cell of origin = neuronal

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15
Q

Flexner-Wintersteiner Rosettes

A

Retinoblastoma

small-blue tumor

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16
Q

RB gene

A

tumor suppressor gene
blocks gene transcription
blocks the cell cycle at G1

17
Q

papilledema

A

bilateral
increased ICP
stasis of BF
stasis of axoplasmic transport in optic nerve head

18
Q

glaucomatous optic nerve damage

A

increased IOP –> loss ganglion cells + thinning of retinal nerve fiber layer

advanced cases = optic disc cupped + optic nerve atrophy