Cerebrum (4-8-14) Flashcards

1
Q

tumors in dura matter

A

meningioma

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2
Q

tumors in cerebrum

A

astrocytomas (infiltrating glioma) oligodendroglioma (infiltrating glioma) ganglioglioma

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3
Q

tumors that cross corpus callosum

A

GBM CNS Lymphoma

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4
Q

where do cerebral metastatic neoplasms come from?

A

-any cancer= LUNG, breast, prostate, gi, KIDNEY -Melanoma -Choriocarcinoma

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5
Q

MC location of Infiltrating Gliomas in children?

A

Brainstem OR Thalamus

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6
Q

Astrocytoma, WHO grade II: who gets it?

A

Found in white matter of young adults, 30-40 yrs

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7
Q

Astrocytoma, WHO grade II: imaging?

A

T2-bright but lacks contrast enhancement

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8
Q

Astrocytoma, WHO grade Il: prognosis?

A

extent of resection, neurological status at presentation

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9
Q

Astrocytoma, WHO grade II: survival?

A

> 10 years survival

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10
Q

Anaplastic Astrocytoma, WHO grade III: presentation? imaging? survival?

A

Presents 10 years later than Grade II Often enhance in focal or patchy pattern 2-4 year survival

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11
Q

Glioblastoma Multiforme (GBM), WHO grade IV -age? -imaging? -survival?

A

-Peak incidence 50-60 years -Neoplasm occupies both hemispheres through the corpus callosum -Irregular ring enhancing -Average 1 year survival

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12
Q

Pleomorphic Xanthoastrocytoma (PXA) -age? -location? -imaging?

A

Generally in children and young adults Typically supratentorial cortex (temporal lobe, superficial) MRI: well circumscribed/cystic

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13
Q

Oligodendroglioma: genetics? microscopic?

A

loss of chromosomes 1p,19q Perinuclear halos Delicate capillaries Calcification

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14
Q

Primary CNS lymphoma

A

Elder individual -Diffuse large B-cell lymphoma, enhancing (without necrosis) MRI In HIV positive individual -Diffuse large B-cell lymphoma, LMPEBV +, ring enhancing MRI WITH necrosis

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15
Q

Periventricular Neoplasms

A

Ependymomas Central neurocytomas Colloid cyst

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16
Q

Ependymoma -who gets it? -location?

A

Both children and adults 4th ventricle=child Spinal cord = adult

17
Q

Central Neurocytoma

A

Young adults that present with acute increase in intracranial pressure Non-infiltrating low grade tumors, WHO II Rare tumors that arise from neoplastic neurons

18
Q
A

Astrocytoma, WHO grade II

19
Q
A

Diffuse Astrocytoma, WHO Grade II

20
Q
A

Diffuse Astrocytoma, WHO Grade II

21
Q
A

Anaplastic Astrocytoma, WHO grade III

22
Q
A

Anaplastic Astrocytoma, Grade III

23
Q
A

Glioblastoma Multiforme, Grade IV

24
Q
A

GBM “Butterfly Lesion”

25
Q
A

GBM

26
Q
A

GBM

27
Q
A

Pleomorphic Xanthoastrocytoma

28
Q
A

Pleomorphic Xanthoastrocytoma

29
Q
A

Oligodendroglioma

30
Q
A

Oligodendroglioma

31
Q

A

CNS Lymphoma

32
Q
A

CNS Lymphoma

33
Q
A

Ependymoma

34
Q
A

Ependymoma

35
Q
A

Ependymoma

36
Q
A

Central Neurocytoma

looks just like Oligodendroglioma, won’t be asked to distinguish