Cerebrum (4-8-14) Flashcards
tumors in dura matter
meningioma
tumors in cerebrum
astrocytomas (infiltrating glioma) oligodendroglioma (infiltrating glioma) ganglioglioma
tumors that cross corpus callosum
GBM CNS Lymphoma
where do cerebral metastatic neoplasms come from?
-any cancer= LUNG, breast, prostate, gi, KIDNEY -Melanoma -Choriocarcinoma
MC location of Infiltrating Gliomas in children?
Brainstem OR Thalamus
Astrocytoma, WHO grade II: who gets it?
Found in white matter of young adults, 30-40 yrs
Astrocytoma, WHO grade II: imaging?
T2-bright but lacks contrast enhancement
Astrocytoma, WHO grade Il: prognosis?
extent of resection, neurological status at presentation
Astrocytoma, WHO grade II: survival?
> 10 years survival
Anaplastic Astrocytoma, WHO grade III: presentation? imaging? survival?
Presents 10 years later than Grade II Often enhance in focal or patchy pattern 2-4 year survival
Glioblastoma Multiforme (GBM), WHO grade IV -age? -imaging? -survival?
-Peak incidence 50-60 years -Neoplasm occupies both hemispheres through the corpus callosum -Irregular ring enhancing -Average 1 year survival
Pleomorphic Xanthoastrocytoma (PXA) -age? -location? -imaging?
Generally in children and young adults Typically supratentorial cortex (temporal lobe, superficial) MRI: well circumscribed/cystic
Oligodendroglioma: genetics? microscopic?
loss of chromosomes 1p,19q Perinuclear halos Delicate capillaries Calcification
Primary CNS lymphoma
Elder individual -Diffuse large B-cell lymphoma, enhancing (without necrosis) MRI In HIV positive individual -Diffuse large B-cell lymphoma, LMPEBV +, ring enhancing MRI WITH necrosis
Periventricular Neoplasms
Ependymomas Central neurocytomas Colloid cyst