Basal Ganglia 3/10/14

Question 1

what is included in the corpus striatum “striped body”?

Answer 1

caudate nucleus

putamen

Question 2

What is included in the lentiform nucleus?

Answer 2

Putamen

Globus pallidus

Question 3

what does the corpus striatum develop from?

Answer 3

telencephalon

Question 4

what does the globus pallidus develop from?

Answer 4

diencephalon

Question 5

What is the input zone of the basal ganglia?

Answer 5

Corpus Striatum

• caudate nucleus
• putamen

Question 6

in ____ disease, striatal neurons in the caudate and putamen degenerate. This causes a removal of inhibition from the ______ nucleus

Answer 6

Huntington’s Disease

removal of inhibition from the subthalamic nucleus

Question 7

What is the HD gene? What repeat sequence is there? How many repeats are needed for HD?

Answer 7

Chromosome 4p

CAG repeat sequence of 36+ (normal = 26)

Question 8

what is tardive dyskinesia?

Answer 8

• movement disorder –> rapid movements of: mouth, tongue, limbs
• secondary cause: medications –> changes in dopamine transmission

Question 9

methanol intoxication affects the…

Answer 9

putamen

Question 10

carbon monoxide poisoning affects the…

Answer 10

globus pallidus