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Dispensing F13 Exam II > Medications for Impotence > Flashcards

Medications for Impotence Flashcards

0
Q

warning for impotence medications

A

go to ER if erection lasts 4 or more hours

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1
Q

impotence

A

erectile dysfunction

-common in diabetic men

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2
Q

Yocon

A

yohimbine

  • FDA approved vitamin ind. for impotence
  • tablet: 5.4mg
  • daily dose = 42mg/day, 3 tabs TID
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3
Q

Caverject Powder

A

alprostadil

  • prostaglandin, vasodilator: relaxes smooth muscle in the penis and increases blood flow
  • onset in mins, DOA: 1hr
  • max of 3 per week
  • 20mcg, 40mcg single use vials
  • first injection must be done in DR office and must stay until erection is gone
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4
Q

detumescence

A

subsiding erection

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5
Q

MUSE

A

alprostadil

  • prostaglandin, vasodilator
  • onset: 5-10min, DOA: 1 hr
  • 250mcg, 500mcg, 1000mcg
  • refrigerate in pharmacy; pt. may leave at RT for 14 days
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6
Q

MUSE pt. counseling

A
  • urinate prior to insertion because residual urine will help dissolve the pellet
  • once inserted, push button to release pellet and rock back and forth upon removal
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7
Q

phosphodiesterase inhibitors (5)

A 
Viagra
Levitra
Staxyn
Cialis
Stendra
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8
Q

MOA for phosphodiesterase inhibitors

A
  • nitric oxide (NO)- a substance released in men when sexually aroused, it activates guanylate cyclase and increases the synthesis of cyclic guanosine monophosphate, cGMP relaxes smooth muscle in the penis allowing increased blood flow into the penis
  • NO is metabolized by PDE, so inhibition of PDE allows for a longer erection
  • drugs only work if man is sexually aroused because NO must be present
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9
Q

PDE

A

phosphodiesterase

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10
Q

pt. counseling for PDEIs

A
  • all PDEIs except Cialis: take 1 hr prior to sexual activity
  • drug interactions: nitrates (nitroglycerin and isosorbide) and alpha-1 blockers
  • adverse effects:
  • -headache(Viagra has highest incidence)
  • -flushing(due to vasodilation)
  • -alter color vision(Viagra makes things look blue)
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11
Q

Viagra

A

sildenafil

  • phosphodiesterase inhibitor
  • tablet: 25mg, 50mg, 100mg
  • discovered as adverse effect for angina drug
  • take on ES*
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12
Q

Levitra

A

vardenafil

  • phosphodiesterase inhibitor
  • tablet: 2.5mg, 5mg, 10mg, 20mg
  • take on ES*
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13
Q

Staxyn

A

vardenafil

  • phosphodiesterase inhibitor
  • ODT: 10mg
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14
Q

Cialis

A

tadalafil

  • phosphodiesterase inhibitor
  • also ind. for symptoms of BPH (5mg qday)
  • tablet: 2.5mg, 5mg, 10mg, 20mg
  • do NOT take with alpha-1 inhibitors because it can cause severe hypotension
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15
Q

Stendra

A

avanafil

  • phosphodiesterase inhibitor
  • 50mg, 100mg, 200mg
  • originally discovered when developing BP med
16
Q

Cialis dosing

A
  • can be taken without regard to meals because it has a 36 hour window of efficacy
  • should take like a maintenance drug: suggested BIW or 2.5mg or 5mg qday

Dispensing F13 Exam II (18 decks)

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