Alpha-1 Adrenergic Blocking Agents Flashcards
0
Q
Minipress
A
prazosin
- alpha-1 adrenergic blocking agent
- ind. ONLY for HTN
1
Q
alpha-1 adrenergic blocking agents (7)
A
-may cause syncope with first few doses or dose increase, so take at bedtime Minipress terazosin Cardura Flomax Uroxatral Rapaflo Jalyn
2
Q
terazosin
A
- alpha-1 adrenergic blocking agent
- ind. for HTN and BPH symptoms
3
Q
Cardura
A
doxazosin
- alpha-1 adrenergic blocking agent
- ind. for HTN and BPH symptoms
4
Q
MOA of terazosin and Cardura
A
- Tx HTN by blocking alpha-1 receptors on the blood vessels, causing them to dilate
- Tx BPH symptoms by blocking alpha-1 receptors in the bladder neck to improve outflow of urine (do NOT reduce prostate size)
5
Q
What drugs can shrink the size of the prostate?
A
5-alpha reductase inhibitors
-inhibit the enzyme 5-alpha reductase to prevent the conversion of testosterone to dihydrotestosterone (DHT) which causes prostate enlargement
6
Q
Proscar
A
finasteride 5mg tablet
- 5-alpha reductase inhibitor
- ind. for reduction of prostate size
7
Q
Avodart
A
dutasteride
- 5-alpha reductase inhibitor
- ind. for reduction of prostate size
8
Q
Propecia
A
finasteride 1mg tablet
- 5-alpha reductase inhibitor
- ind. for alopecia
9
Q
alopecia
A
baldness
10
Q
warning about 5-alpha reductase inhibitors
A
pregnant women should not handle these because they can be absorbed through the skin and affect the child
11
Q
Flomax
A
tamsulosin
- alpha-1 adrenergic blocking agent
- ind. ONLY for BPH symptoms
12
Q
Uroxatral
A
alfuzosin
- alpha-1 adrenergic blocking agent
- ind. ONLY for BPH symptoms
13
Q
Rapaflo
A
silodosin
- alpha-1 adrenergic blocking agent
ind. ONLY for BPH symptoms
14
Q
Jalyn
A
dutasteride, tamsulosin
- 5-alpha reductase inhibitor, alpha-1 adrenergic blocking agent
- reduces prostate size AND blocks receptors in bladder neck
