Isotretinoin Flashcards
0
Q
pt. counseling for isotretinoin
A
- avoid in pregnancy
- all contain soybean oil: if allergic to peanuts, do not take isotretinoin
- take WITH food
- may cause phototoxic reactions
- do not donate blood until off isotretinoin for at least 30 days
- causes hypertriglyceridemia, cheilitis, epistaxis, xeroderma: all approximately 90%
- use cautiously in pts. with psychiatric disorders
1
Q
Amnesteem, Claravis, Sotret
A
isotretinoin
- category: antiacne, class: retinoid
- used to be Accutane
- ind. for severe acne unresponsive to other Tx
- 10mg, 20mg, 40mg BID: usually taken for about 3 months
- extremely teratogenic*
2
Q
cheilitis
A
inflammation of lips
3
Q
epistaxis
A
nose bleeds
4
Q
xeroderma
A
dry skin
5
Q
iPLEDGE
A
program started to lower the incidence of birth defects associated with isotretinoin
6
Q
teratogen
A
agent that causes birth defects
7
Q
isotretinoin MOA
A
reduces sebum production, which is produced by sebaceous glands
