Medical Complications in Pregnancy Flashcards

1
Q

what is APLS?

A

acquired thrombophilia that produces autoantibodies thatreact to phospholipid component of the cell membrane

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2
Q

presentation of APLS

A
arterial/ venous thrombosis
recurrent pregnancy loss
placental abruption
early onset PET
early onset FGR
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3
Q

diagnosis of APLS

A

IgM/IgG aCL and LA >6 weeks apart

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4
Q

management of APLS

A

aspirin + LMWH

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5
Q

seizures in pregnancy

A
  • Intra-partum= BZDs
  • If no seizure history, then give magnesium sulphate (eclampsia)
  • Safety post-natally e.g. avoid fatigue, safe feeding, bathing, pram brake
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6
Q

what is obstetric cholestasis?

A

disorder of the liver that causes build-up of bile acids

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7
Q

presentation of obstetric cholestasis

A

itch without rash

jaundice

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8
Q

weekly monitoring of what in obstetric cholestasis?

A

LFTs
bile acid
USS

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9
Q

management of obstetric cholestasis

A

emollients
antihistamines
ursodeoxycholic acid
vitamin K

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10
Q

when to induce obstetric cholestasis

A

offered at 37 weeks

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11
Q

why does obstetric cholestasis increase the risk of PPH?

A

vitamin K malabsorption

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