Medical Complications in Pregnancy Flashcards
what is APLS?
acquired thrombophilia that produces autoantibodies thatreact to phospholipid component of the cell membrane
presentation of APLS
arterial/ venous thrombosis recurrent pregnancy loss placental abruption early onset PET early onset FGR
diagnosis of APLS
IgM/IgG aCL and LA >6 weeks apart
management of APLS
aspirin + LMWH
seizures in pregnancy
- Intra-partum= BZDs
- If no seizure history, then give magnesium sulphate (eclampsia)
- Safety post-natally e.g. avoid fatigue, safe feeding, bathing, pram brake
what is obstetric cholestasis?
disorder of the liver that causes build-up of bile acids
presentation of obstetric cholestasis
itch without rash
jaundice
weekly monitoring of what in obstetric cholestasis?
LFTs
bile acid
USS
management of obstetric cholestasis
emollients
antihistamines
ursodeoxycholic acid
vitamin K
when to induce obstetric cholestasis
offered at 37 weeks
why does obstetric cholestasis increase the risk of PPH?
vitamin K malabsorption