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Obstetrics and Gynaecology > 4th Year Pharmacology > Flashcards

4th Year Pharmacology Flashcards

1
Q

what is syntocinon?

A

synthetic oxytocin

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2
Q

role of syntocinon

A

increases contractions of uterine smooth muscle so used to induce/augment labour and PPH

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3
Q

cautions in syntocinon

A

bolus can cause hypotension and tachycardia

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4
Q

what is ergometrine?

A

adrenergic, dopaminergic, 5-HT2 receptor agonist

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5
Q

role of ergometrine

A

increases contraction of uterine smooth muscle and used in PPH

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6
Q

cautions in ergometrine

A

asthma

hypertension

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7
Q

what is carboprost?

A

synthetic prostaglandin F2a

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8
Q

role of carboprost?

A

increases contraction of uterine smooth muscle and is used in PPH

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9
Q

adverse of carboprost?

A

bronchoconstriction

hypertension/cardiac

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10
Q

what is misoprostol?

A

synthetic prostaglandin E1 analogue used in PPH, termination and miscarriage

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11
Q

caution in misoprostol

A

caution in asthmatics

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12
Q

what is prostin E2/ propess dinoprostone?

A

prostaglandin E2

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13
Q

what does prostin E2/ propess dinoprostone do?

A

cervical effacement

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14
Q

adverse of prostin E2/ propess dinoprostone?

A

uterine hyperstimulation

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15
Q

what is nifedipine?

A

CCB

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16
Q

use of nifedipine in pregnancy

A

tocolytic that reduces contraction of uterine smooth muscle

17
Q

when to avoid nifedipine

A

aortic stenosis or coarctation

18
Q

what is magnesium sulphate?

A

naturally occurring mineral

19
Q

role of magnesium sulphate

A

smooth muscle relaxation used in eclampsia and protection of neonatal brain

20
Q

adverse of magnesium sulphate

A

hypotonia and resp depression

21
Q

when to beware of use of magneisum sulphate?

A

urine <100ml in 4 hours
deep tendon reflexes absent
RR <10

22
Q

UTI management in pregnancy

A
  • 1st + 2nd tri is nitrofurantoin
  • 3rd trimethoprim

2nd line in any tri is cefalexin

23
Q

antibiotics for sepsis in pregnancy

A

amox

clind or co-trimox

Obstetrics and Gynaecology (31 decks)

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