Medicaions For Peds Hematology Flashcards
Chelating agents (beta thalassemia)
Desferal (deferoxamine)
Ex jade (deferasirox)
Route for desferal (deferoxmine)
IM or IV at infusion center
SQ
What do we want to educate parents about chelating agents
1)They. Bind to iron and excrete thru the urine so it may turn urine orange or the color of Rust
2) yearly hearing& vision screening ( chelation can cause issues)
3) if parents notice issues notify practitioner immediately
What vit do we need to help chelators? (Beta thalassemia)
Vit C (helps pull iron from tissues (from liver). and into blood so chelators can attach to iron then excrete)
SQ chelators desferal deferroxamine
Teach parents- Portable infusion pump given over 8 hr (done over night)
4- 6 nights a wk
Po MED for chelation med (beta thalassemia)
Ex jade (deferasirox )
Po to children OLDER than 2
DO NOT GIVE TO CHILD UNDER 2
Chelation for BLL that is > or equal to 45 mcg/dl
Succimer (chemet)
Capsule or sprinkle
PO daily for 19 days
Other chelation for symptoms of lead poisoning
Calcium di sodium (EDT) IM
What is something we want to teach about calcium di sodium (EDTA)
Very painful when administered IM so use emla
Teach to rotate IM site
T or f multiple treatments of lead poisoning are not necessary
False
Multiple treatments are necessary
Give , test blood level and repeat as needed
What two interventions regarding splenectomy will we keep in mind
The patient will be on prophylactic medication 4 Eva due to increase risk of infection
Routine immunizations (keep up to date)
What is important to note about chelation when it comes to treatment of BLL > or equal to 45
Given to protect the kidney but will not reverse or counteract effects that have taken place like CNS involvement
Drug that is used for mills factor 8 deficiency
DDAVP synthetic vasopressin
Medication treatments for ITP (immune thrombocytopenia)
Prednisone
immune globulin (IVIG),
anti-d antibody (WINRHO)
What will the medication treatments do for ITP
Not going to cure but will decrease spleen activity that is destroying platelets
Treatment for chronic ITP
Splenectomy
At what age is a splenectomy done for chronic ITP
Wait till 5 or older due to risk of bacterial infection and sepsis
What is prescribed for prophylaxis splenectomy
Penicillin prophylaxis
What therapy is given too pregnant mothers with HIV?
ART
(Antiretroviral therapy)
Elisa or western blot
HIV test to determine in 18 mo or older
HIV polymerace chain reaction
More specific test for children under the age of 18 mo
Med therapy for HIV
ART (lifelong)
IV gamma globulin (IVIG)
Combo med Prophylactic antibiotic HIV
Trimethoprim-Sulflanethoxazole
(Bactrum)
Primary treatment for leukemia
Chemo therapy
Retinoblastoma treatment
Laser treatment
Cryotherapy (cold)
Chemo or radiation (depending on stage)
Enuleation surgery
Wilms tumor nephroblastoma treatment
Chemo maybe radiation
Surgery -removal of kidney tumor adrenal gland removed
Neuroblastoma treatment
Chemo main treatment
Radiation may be recommended
Phase one of chemo
Goal - remission and re
Serotonin receptor antagonist before chemo
N&V
Ondansetron (zofran)
Granisetron(kytil)
Aprepitant (emend)
( administered 1 hr before chemo & often combined w dexmethasone)
