Medicaions For Peds Hematology

Question 1

Chelating agents (beta thalassemia)

Answer 1

Desferal (deferoxamine)
Ex jade (deferasirox)

Question 2

Route for desferal (deferoxmine)

Answer 2

IM or IV at infusion center
SQ

Question 3

What do we want to educate parents about chelating agents

Answer 3

1)They. Bind to iron and excrete thru the urine so it may turn urine orange or the color of Rust

2) yearly hearing& vision screening ( chelation can cause issues)

3) if parents notice issues notify practitioner immediately

Question 4

What vit do we need to help chelators? (Beta thalassemia)

Answer 4

Vit C (helps pull iron from tissues (from liver). and into blood so chelators can attach to iron then excrete)

Question 5

SQ chelators desferal deferroxamine

Answer 5

Teach parents- Portable infusion pump given over 8 hr (done over night)
4- 6 nights a wk

Question 6

Po MED for chelation med (beta thalassemia)

Answer 6

Ex jade (deferasirox )
Po to children OLDER than 2
DO NOT GIVE TO CHILD UNDER 2

Question 7

Chelation for BLL that is > or equal to 45 mcg/dl

Answer 7

Succimer (chemet)
Capsule or sprinkle
PO daily for 19 days

Question 8

Other chelation for symptoms of lead poisoning

Answer 8

Calcium di sodium (EDT) IM

Question 9

What is something we want to teach about calcium di sodium (EDTA)

Answer 9

Very painful when administered IM so use emla
Teach to rotate IM site

Question 10

T or f multiple treatments of lead poisoning are not necessary

Answer 10

False
Multiple treatments are necessary
Give , test blood level and repeat as needed

Question 11

What two interventions regarding splenectomy will we keep in mind

Answer 11

The patient will be on prophylactic medication 4 Eva due to increase risk of infection
Routine immunizations (keep up to date)

Question 12

What is important to note about chelation when it comes to treatment of BLL > or equal to 45

Answer 12

Given to protect the kidney but will not reverse or counteract effects that have taken place like CNS involvement

Question 13

Drug that is used for mills factor 8 deficiency

Answer 13

DDAVP synthetic vasopressin

Question 14

Medication treatments for ITP (immune thrombocytopenia)

Answer 14

Prednisone
immune globulin (IVIG),
anti-d antibody (WINRHO)

Question 15

What will the medication treatments do for ITP

Answer 15

Not going to cure but will decrease spleen activity that is destroying platelets

Question 16

Treatment for chronic ITP

Answer 16

Splenectomy

Question 17

At what age is a splenectomy done for chronic ITP

Answer 17

Wait till 5 or older due to risk of bacterial infection and sepsis

Question 18

What is prescribed for prophylaxis splenectomy

Answer 18

Penicillin prophylaxis

Question 19

What therapy is given too pregnant mothers with HIV?

Answer 19

ART
(Antiretroviral therapy)

Question 20

Elisa or western blot

Answer 20

HIV test to determine in 18 mo or older

Question 21

HIV polymerace chain reaction

Answer 21

More specific test for children under the age of 18 mo

Question 22

Med therapy for HIV

Answer 22

ART (lifelong)
IV gamma globulin (IVIG)

Question 23

Combo med Prophylactic antibiotic HIV

Answer 23

Trimethoprim-Sulflanethoxazole

(Bactrum)

Question 24

Primary treatment for leukemia

Answer 24

Chemo therapy

Question 25

Retinoblastoma treatment

Answer 25

Laser treatment
Cryotherapy (cold)
Chemo or radiation (depending on stage)
Enuleation surgery

Question 26

Wilms tumor nephroblastoma treatment

Answer 26

Chemo maybe radiation
Surgery -removal of kidney tumor adrenal gland removed

Question 27

Neuroblastoma treatment

Answer 27

Chemo main treatment
Radiation may be recommended

Question 28

Phase one of chemo

Answer 28

Goal - remission and re

Question 29

Serotonin receptor antagonist before chemo
N&V

Answer 29

Ondansetron (zofran)
Granisetron(kytil)
Aprepitant (emend)

( administered 1 hr before chemo & often combined w dexmethasone)