Med Surg-Quiz 6 Flashcards
foreign body that does not have the characteristics of “self” cell surface markers. Each body’s “self” surface markers are unique like a handprint. Mine is not the same as yours. They may look the same, but when examined more, each has a different line pattern or characteristic that makes it unique.
Antigen
histocompatibility markers to identify as “self.”
Human Leukocytic Antigens – (HLA’s)
What are the two basic types of immunity:
innate and acquired
the body’s first line of defense. Nonspecific responses to invaders. Same response every time. Lacks a memory. Gene specific.
Innate
- Skin
- Tears
- Ear wax
- Nasal hairs
- Stomach acids
- Vaginal secretions
- Acidic urine
Examples of Innate Immunity
has specificity and memory
Acquired Immunity
What are the 5 types of antibodies?
IgM, IgG, IgA, IgD, IgE
Initial immune response. Largest size. Activates the complement system. Responsible for blood type matching
IgM
Found in blood. Crosses the placenta to protect newborns by
passive immunity. Activates the complement system.
IgG
Innate Immunity: found in saliva, mucus membranes, tears, etc. Defends external body surfaces.
IgA
Antigen receptor. Found on B-lymphocytes.
IgD
Eliminates parasitic invaders. Releases histamine. Normal response until becomes excessive due to allergies and causes anaphylactic shock. (Link the “E” to the role of epi-pens)
IgE
What are the 4 purposes of Immunoglobulins?
- directly attack antigens
- activate the complement system
- release histamine
- stimulate hypersensitivity reaction
“Grave Muscular weakness” Impaired reception of the ACh (acetylcholine) molecule at the neuromuscular connection. This reception is needed to stimulate an action potential to create a muscle contraction.
Myasthenia Gravis
Signified by a facial rash (Butterfly rash)
Auto-Antibodies circulate and destroy multiple systems in the body. Different for each patient.
Systemic Lupus Erthyematosus