Med Surg-Quiz 4 Flashcards
What is Ischemia?
critical reduction of oxygen supply to the cell due to a blood supply that is less than the minimum required for homeostasis.
What is hypoxia?
partial loss of oxygen circulation
What is anoxia?
complete loss of oxygen circulation
What is atrophy?
“a reduction in cell and organ size.”
What is hypertrophy?
Defined as: “an increase in the size of the cell and organ. Can only occur in heart and striated muscles 2⁰ these cells cannot divide…Hypertrophy of the heart is associated with CHF. (Congestive Heart Failure)
What is hyperplasia?
Defined as: “an increase in the number of cells leading to increased organ size.” Due to ability of cell division. Examples: thickening of the uterine lining, and skin calluses.
What is metaplasia?
Defined as: “a change in cell morphology and function resulting from the conversion of one adult cell type into another.”Example: adaptation of smokers. Lining of the trachea/bronchi changes from a ciliated pseudostratified columnar epithelium to striated squamous epithelium which makes it more difficult to have a productive cough. Stuff sticks to the trachea rather than being moved along by the cilia.
What is dysplasia?
Defined as: an increase in cell numbers that is accompanied by altered cell morphology and loss of histologic organization. Found in areas that are chronically injured and responding to increased demands. (Example: what PAP smears are screening for…)Considered a pre-cancer condition.Example: chronic reflux irritates lining of esophagus or other tissues in the throat; leads to cell dysplasia which can convert to throat cancer!
What is neoplasia?
Defined as: “the development of neoplasms.” Neoplasms are defined as: “a new and abnormal formation of tissue, as a tumor or growth. It serves no useful function, but grows at the expense of the healthy organisms.” (Taber’s Cyclopedic Medical Dictionary)This is synonymous with cancer cells.Benign- do not metastasize, typically not life threatening.Malignant- cells are undifferentiated and nonfunctional. Tend to multiply quickly. Risk for metastasis.
What is the tissue healing process after injury?
Three phases of healing: inflammation, proliferation, and maturation. *Each phase has 3-4 stages within itself.
What is the process of inflammation?
4 Cardinal Signs
Heat (calor)Redness/Erythema (rubor)3. Swelling/Edema (tumor)4. Pain (dolor) #1 & 2 are primarily due to vasodilation and hyperemia #3 & 4 are primarily due to increased capillary permeability
What are chemical mediators?
substances that cause, or stimulate, the reactions needed to begin the process of inflammation
What is chemotaxis?
attraction of cells, causing them to come together, as needed for tissue healing
What is phagocytosis?
ingestion and digestion of bacteria and particles by a cell.
What is a neutrophil?
WBC that performs initial chemotaxis and phagocytosis.
What is a lysosome?
a separate particle in the cell that acts as the cell’s digestive system.
What is a macrophage?
larger cell that performs phagocytosis once neutrophils are exhausted
What is transudate?
first form of edema. Contains very few cells or proteins. Mostly clear liquid.