Mechanisms of Acute Neuronal Injury Flashcards

0
Q

Cytotoxic edema

A

Occurs when ATP stores are deplete and membrane ionic permeability is too high

-Neuronal ATP dependent upon continuous supply of O2 and glucose

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1
Q

NMDA receptor characteristics

A
  1. Activation requires glycine
  2. Dually gated by glutamate and membrane potential
  3. Permeable to Ca2+
    - Also contains a Mg2+ binding site that blocks ion flow when bound
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