Mechanisms of Acute Neuronal Injury Flashcards
0
Q
Cytotoxic edema
A
Occurs when ATP stores are deplete and membrane ionic permeability is too high
-Neuronal ATP dependent upon continuous supply of O2 and glucose
1
Q
NMDA receptor characteristics
A
- Activation requires glycine
- Dually gated by glutamate and membrane potential
- Permeable to Ca2+
- Also contains a Mg2+ binding site that blocks ion flow when bound