Behavior of Addiction Flashcards
Sensitization
Repeated use of the drug elicits an escalating result
- Can lead to bruxism, tics
- Can have cross-sensitization where one drug increases effect of other
Dependence
Need for continued drug exposure to avoid withdrawl
Type 1 Cloninger
Alcoholism occurs later in life; typically due to environmental factors
Typer II Cloninger
Alcoholism occurs earlier in life; usually seeking alcohol for novelty reasons
Moral Model of Addiction
Addiction stems from human weakness and is reprehensible
-Punishable
Temperance Model of Addiction
Drug itself is the problem
Treatment goal=abstinence
Disease Model of Addiction
Neurobiological changes in behavior cause addiction
Psychological Model of Addiction
Addictive personality of a person who is insecure, egocentric
Treatment= Reconstruction of person’s personality
Social Model of Addiction
Addiction is a learned behavior due to poor socialization
Treatment= Appropriate modeling
Brain Stimulation Reward Model of Addiction
Stimulation of pleasure centers in the brain award it for drug use
Synergy
Addiction of one drug or activity coincides w/ the addiction of another
-Smoking after sex
What is the most powerful priming stimulus for a drug?
Tasting it
Cue
induced reinstatement involving dopamine modulation in the basolateral amygdala and a glutaminergic projection to the nucleus accumbens
Craving Type 1
Caused by impulsive acts reaching an award or “cue” followed by regret
Craving Type II
Negative enforcement that seeks drugs to relieve anxiety resulting in obsession
-Involves CRF and NE in amygdala
