Mar1 M1-Diabetes Prevention Flashcards
gestational diabetes pathophgy
insulin resistance
diabetes prevalence dx vs prevalence overall
prevalence dx = 7% pop
prevalence overall = 13%
kids epi of diabetes
type 1 most common. type 2 incidence rising
gestational diabetes charact
- higher phgy demand of sugar
- resolves postpartum
- strong risk factor for future type 2 DM
prediabetes prevalence
third of adults. strong risk factor. type 2 DM predictor
DM values for dx
fasting = over 7
2 hr after 75g = over 11.1
AIC over 6.5%
GDM dx
- 75g oral test
- fasting = over 5.1
- 1 hour after meal = over 10
- 2 hr after meal = over 8.5
main complications of diabetes (5)
- retinopathy
- kidney failure
- stroke
- heart disease
- amputations
GDM management
have to treat it
why treat GDM
-neonate can have growth problem (macrosomia = large baby). insulin is a growth hormone (remember GDM = insulin resist so higher insulin)
associations of GDM
- postpartum diabetes in mom (**added risk with gestational htn)
- diabetes in fathers
expensive test for diabetes
insulin-glucose ratio in blood (tells for insulin resist) (HOMA-IR test. over 2 = insulin resistance)
most important time in diabetes prevention
prediabetes period. is most responsive to change (lifestyle, etc.)
general principles for preventing T2DM, GDM and prediabetes
-weight loss
-phys activity
-improved dietary quality
-metformin, acarbose
TO REDUCE INSULIN RESISTANCE
american diabetes prevention program in pts with impaired glucose: they tried to prescribe what
7% weight loss
150 minutes activity each week
850 mg metformin twice daily