Mannheimia and Bibersteinia

Question 1

What differentiates Mannheimia haemolytica and Bibersteinia trehalosi?

Answer 1

Mannheimia haemolytica is trehalose negative, while Bibersteinia trehalosi is trehalose positive

Question 2

________ is the most important bacterial cause of respiratory disease in cattle and sheep

Answer 2

Mannheimia haemolytica

Question 3

______ has also been associated with mastitis in sheep

Answer 3

Mannheimia haemolytica

Question 4

What do the colonies of Mannheimia haemolytica look like?

Answer 4

They are smaller than P. multocida and do not have the same distinct musty odor
Also have a very distinct, thin zone of complete hemolysis

Question 5

T/F All types of Mannheimia haemolytica produce cytotoxins

Answer 5

TRUE; this is also true for Bibersteinia trehalosi

Question 6

The cytotoxin produced by Mannheimia haemolytica is toxic for ________

Answer 6

leukocytes and platelets of ruminants

Question 7

The cytotoxin of Mannheimia haemolytica is considered a ______ toxin

Answer 7

RTX; punches holes in teh cell membrane

Question 8

Low levels of M. haemolytica toxin ______ while high levels lyse the ________ completely

Answer 8

Affect the function of leukocytes

Leukocytes

Question 9

Where is the normal habitat for Mannheimia haemolytica?

Answer 9

Upper respiratory tract of cattle and sheep

Question 10

Transmission of Mannheimia haemolytica?

Answer 10

ingestion or inhalation; Inhalation is the most common

Question 11

What is the form of Mannheimia haemolytica that affects cattle?

Answer 11

Biovar A serotype 1

Serotype 2 is also seen, but it is non-pathogenic

Question 12

_____% of feedlot pneumonia cases are due to Mannheimia haemolytica biovar A serotype 1

Answer 12

90

Question 13

What lesions do you see with Mannheimia haemolytica biovar A serotype 1 infections in cattle?

Answer 13

fibrinous pleuropneumonia that can be involved with shipping fever complex

Question 14

Mannheimia haemolytica can be an important cause of _____ in sheep. It is referred to as blue bag, as it can become gangrenous

Answer 14

mastitis

Question 15

T/F Mannheimia haemolytica is an important organism in swine and horse health as well

Answer 15

FALSE; isolated occasionally but nothing to call home about

Question 16

T/F Killed bacterins provide sufficient immunity against Mannheimia hemolytica

Answer 16

TRUE; they need to be given early and have to be given twice

Question 17

A normal, non-stressed calf is able to withstand low levels of ________

Answer 17

Mannheimia haemolytica

Question 18

______ cells are very important in the lower respiratory tract for defense

Answer 18

Phagocytic

Question 19

High numbers of Mannheimia haemolytica in the lung may allow the organism to ______ and cause severe _______

Answer 19

survive

pneumonia

Question 20

Mannheimia haemolytica _____ is thought to be important in the development of pneumonia

Answer 20

cytotoxin

Question 21

Understand why the leukotoxin of Mannheimia haemolytica can cause pneumonia

Answer 21

Basically it lyses leukocytes, which causes the release of lysosomal enzymes, which causes inflammation in the lung
Inflammed lung tissue is non-functional lung tissue

Question 22

A successful humoral response against Mannheimia haemolytica requires antibody against what two things?

Answer 22

1: the cytotoxin; Can be IgA, IgM, or IgG
2: Cell surface components; efficient killing of the organism

Question 23

______ is an organism that is very similar to Mannheimia haemolytica and produces an identical cytotoxin

Answer 23

Biberstieinia trehalosi

Question 24

Bibersteinia trehalose is associated with ______ in dairy cattle, especially in the _______ portion of the US

Answer 24

severe respiratory disease

Northwest

Question 25

Bibersteinia trehalosi causes _______ in feeder lambs

Answer 25

septicemia

Question 26

Bibersteinia trehalosi enters the body via lesions in the _______

Answer 26

esophagus

Question 27

In some areas of the country, __________ has become the most isolated organism from goats with respiratory disease

Answer 27

Bibersteinia trehalosi