Actinobacillus Flashcards

1
Q

What are the Actinobacillus species we are concerned with? (7)

A
Actinobacillus lignieresii
Actinobacillus equuli
Actinobacillus pleuropneumoniae
Actinobacillus suis 
Actinobacillus salpingitidis 
Actinobacillus seminis 
Actinobacillus actinomycetemcomitans
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2
Q

Actinobacillus lignieresii commonly causes ______________ in the head and neck area of cattle

A

granulomatous, tumor like infections

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3
Q

The natural habitat of Actinobacillus ligniersii

A

commensal of the buccal cavity of cattle and sheep

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4
Q

Cattle: how does Actinobacillus ligniersii enter the tissues?

A

Via penetrating wound in the buccal cavity

Often caused by forage

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5
Q

Granulomatous abscesses caused by Actinobacillus ligniersii is often seen where?

A

lower jaw and neck area

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6
Q

T/F Actinobacillus ligniersii will stay localized in the area of infection

A

FALSE; has the ability to cause granulomatous abscesses in other organs; commonly seen in the wall of the stomach

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7
Q

The characteristic lesion of Actinobacillus ligniersii is “______” which is granulomatous abscesses on the tongue drastically reducing function

A

Wooden Tongue

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8
Q

If you were abroad on a trip to Scotland and visitng a sheep farm, what would be a bacteria that would be more commonly seen there than here in the US

A

Actinobacillus ligniersii

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9
Q

T/F Both humoral and CMI immunity is important for Actinobacillus ligniersii infections

A

TRUE

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10
Q

How would you treat an infection of Actinobacillus ligniersii?

A

Localized injections of liquid iodine and IV of sodium iodide

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11
Q

Actinobacillus equuli was formerly in the genus _______. It is the cause of ______ or sleepy foal disease

A

Shigella

Shigellosis

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12
Q

What is teh natural habitat of Actinobacillus equuli?

A

Oral cavity and intestinal tract of normal horses

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13
Q

Describe the pathogenesis of Actinobacillus equuli?

A

It is an opportunist. Only occurs in diseased or debilitated horses. Becomes septicemic and produces an RTX toxin that has leukocytic properties

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14
Q

T/F Actinobacillus can be contracted from the foal passing through the birth canal?

A

TRUE

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15
Q

What is the average lifespan of a foal infected with Actinobacillus equuli?

A

4 days maximum, 1/3 only live to 24 hours

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16
Q

In foals, what are the clinical signs seen with Actinobacillus equuli infections?

A

purrulent nephritis with several abscesses in the renal cortex

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17
Q

In adult horses, Actinobacillus equuli gains entry into the blood via _______ migrating into the blood stream from the intestine

A

Strongylus vulgaris (IT WONT GO AWAY)

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18
Q

Adult horses infected with Actinobacillus equuli often have a _______

A

septicemia

19
Q

T/F There is a commercial vaccine available for Actinobacillus equuli that is commonly used to prevent infections

A

FALSE; there is no commercial vaccine available

20
Q

________ causes contagious pleuropneumonia in swine

A

Actinobacillus pleuropneumoniae

21
Q

T/F Actinobacillus pleuropneumoniae can grow on its own; does not require a growth factor

A

FALSE; growth of this organism requires V factor (NAD

22
Q

What are the three serotypes of Actinobacillus pleuropneumoniae that are present in the US?

23
Q

How many toxins does Actinobacillus pleuropneumoniae produce? What is the name of them? What is the only one that is produced in vivo?

A

4; They are RTX toxins
Apx1, Apx2, Apx3, and Apx4
Apx4 is the only one that grows in vivo

24
Q

What is the natural habitat for Actinobacillus pleuropneumoniae?

A

Upper respiratory tract of swine; Can be shed into the environment by older pigs

25
Describe the pathogenesis of Actinobacillus pleuropneumoniae
usually seen in endemically infected herds. Piglets are infected as colostral immunity wanes, which results in a mild disease. Peracute form can result in pig death in less than 8 hours
26
T/F Actinobacillus pleuropneumoniae does not need an inducing agent
TRUE; this is highly pathogenic
27
Pigs that recover from Actinobacillus pleuropneumoniae are/are not immune to future infections
ARE
28
Treatment of Actinobacillus pleuropneumoniae; does it develop resistance?
Penicillin, tetracycline; YES, it develops resistance relatively easily
29
______ is known to cause acute, fatal septicemia in 1-8 week old pigs
Actinobacillus suis
30
In older pigs, infections with ___________ has been known to cause arthritis, pneumonia, and subcutaneous abscesses
Actinobacillus suis
31
Describe the colonies of Actinobacillus suis
They are relatively small at first, with beta hemolysis. They can grow to be relatively larger compared to other Actinobacillus species
32
What are the RTX toxins that Actinobacillus suis produces?
Apx1 and Apx2
33
Where can Actinobacillus suis be found?
In the tonsils and nasal passages of healthy pigs of ANY age
34
T/F Actinobacillus suis can be found on the vagina of sows
TRUE
35
Infections of Actinobacillus suis mimic infections of what two other organisms?
Actinobacillus pleuropneumoniae and Erysipelothrix rhusiopathiae
36
In young pigs infected with Actinobacillus suis causes _________
septicemia with acute death
37
Is it effective to treat pigs with antibiotics if they are infected with Actinobacillus suis?
Yes, but they usually die before they are able to take effect
38
_______ is an occasional cause of salpingitis and peritonitis in laying hens
Actinobacillus salpingitidis
39
_______ is widespread in sheep in South Africa
Actinobacillus seminis
40
_______ localizes in the epididymis and testes of sheep. It is spread venerally
Actinobacillus seminis
41
Actinobacillus seminis often causes what?
Abortion in sheep | Major problem is decreased fertility in rams
42
________ is implicated in human endocarditis, meningitis, osteomyelitis, and periodontitis
Actinobacillus actinomycetemcomitans (LOL WHAT)
43
The main ecological site of Actinobacillus actinomycetemcomitans is what?
dental plaque, periodontal pockets and gingival sulci