Malignant Neoplasms Flashcards
what is the MC primary malignancy of bone
Multiple myeloma
punched out lesions indicate
MM
Rain drop skull indicates
MM
Test to confirm possible MM
Immunuelctrophoresis
What kind of bone scan does MM have
COLD
4 tests to confirm MM
- M-spike of immunelectrophoresis
- Reversal of A/G ratio
- Bence Jones Protein
- Elevated ESR
swiss cheese appearance in skull indicates
lytic mets
Special test for lytic mets
bone scan
Labs for lytic mets
Alkaline phosphatase
Age for Hodgkins disease
20-40
Ivory white vertebrae with anterior body scalloping at age 20-40 indicates
Hodgkins
Uni-lateral Hilar lymphadenopathy indicates
Hodgkin’s, need biopsy to confirm
When biopsying for Hodgkins what is a Dead GIVE AWAY
Reed Sternberg cells
Ivory white vertebrae in >40y.o.
blastic mets
Alkaline phosphatase is ______ in blastic mets
ELEVATED, use a BONE SCAN to diagnose
Osteitis deformans is aka
Paget’s
Picture frame vertebrae indicates
Paget’s
Banana fractures and bowing deformities are seen commonly with
Paget’s
Cotton wool in skull indicates
Paget’s
Blade of grass look indicates
Paget’s
Ivory vertebrae in 50+ year old
Paget’s most likely
Increased ___________________ ___________ in patients with Paget’s
alkaline phosphatase
Most common malignancy found in children
osteosarcoma 10-30 y.o.
What kind of periosteal reaction occurs in osteosarcoma
spiculated/radiating/sunburst
What kind of bone scan in patient with osteosarcoma
HOT
Osteosarcoma treatment
amputation, chemo, radiation
Chondrosarcoma and Fibrosarcoma age
> 40 y.o. creates a POPCORN matrix, spiculated/radiating/sunburst periosteal reaction
MC found bones for Ewing’s sarcoma
diaphysis of long bones
An onion skin(laminated) periosteal reaction indicates
Ewing’s sarcoma
Age range for Ewing’s sarcoma
10-30
Treatment for Ewing’s sarcoma
amputation, chemo, radiation
Codman’s triangle can be an indication of
Ewing’s sarcoma
what is a Chordoma
aberrant notochordal cell tumor, MC found in the sacrum, 2nd MC is skull
