Male Reproductive Hormones Flashcards

1
Q

Sertoli Cells Function ( 4 )

A
  • Provides nourishment of seminiferous tubules by transporting nutrients to lumen region
  • Carries out phagocytosis by digesting excess cytoplasms and digests germ cells
  • Adds to seminal fluid by synthesising luminal proteins to maintain tubular fluid
  • Hormonal Functions
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2
Q

Hormones Secreted by Sertoli Cells

A

Androgen Binding Protein
Activin
Inhibin

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3
Q

Leydig Cells Synthesises ?

A
  • Testosterone
  • DHT ( dihydrotestosterone )
  • DHEA ( dehydroepiandrosterone )
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4
Q

What does androgen do

A
  • ↑ Spermatogenesis
  • ↑ bone matrix by ↑ calcium deposition
  • Promotes Epiphyseal Closure
  • ↑ Increases Muscle mass
  • ↑ BMR, ↑ RBC density
    ↑ Skin thickness, ↑ melanin deposition, ↑ sebum secretion
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5
Q

Ligand Specific Androgen Activity of Testosterone ?

A

Helps in the descent of testes

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6
Q

Ligand Specific Androgen Activity of DHT ?

A

Stimulates development of external genitalia

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