Drug Induced Renal Failure

Question 1

Prerenal

Answer 1

• Diuretics

- ACE inhibitors

Question 2

Vasoconstriction

Answer 2

• NSAIDs

- Cyclosporine

Question 3

Crystalluria

Answer 3

• Sulfonamides

- Acyclovir

Question 4

Tubular Toxicity

Answer 4

• Aminoglycosides

- Cisplatin

Question 5

Endothelial Injury

Answer 5

• Cocaine

- Oestrogen

Question 6

Glomerularopathy

Answer 6

• Penicillamine

- NSAIDs

Question 7

Interstitial Nephritis

Answer 7

• Antibiotics

- NSAIDs

Question 8

T/F : Drugs bind covalently to proteins to form immunogens

Answer 8

True

Question 9

Drug induced allergic reactions due to ( antibody ? )

Answer 9

Antibody ( Type I - III )

Question 10

Drug induced allergic reaction can be cell mediated ?

Answer 10

Cell mediated ( Type IV )

Question 11

What kind of reaction can penicillin cause ?

Answer 11

Anaphylactic shock

Question 12

What kind of reaction can methyldopa cause ?

Answer 12

Anaemia

Question 13

What kind of reaction can clozapine cause ?

Answer 13

Agranulocytosis

Question 14

What kind of reaction can quinine cause

Answer 14

Thrombocytopenia

Question 15

What do you call an ↑ in RBC

Answer 15

Erythrocytosis

Polycythemia

Question 16

↓ in RBC ?

Answer 16

Anaemia

Erythroblastopenia

Question 17

• ↑ in WBC

- ↓ in WBC

Answer 17

• Leukocytosis

- Leukopenia

Question 18

• ↑ in Lymphocytes

- ↓ in Lymphocytes

Answer 18

• Lymphocytosis

- Lymphocytopenia

Question 19

• ↑ Granulocytes

- ↓ Granulocytes

Answer 19

• Granulocytosis

- Granulocytopenia / Agranulocytosis

Question 20

• ↑ Neutrophils

- ↓ Neutrophils

Answer 20

• Neutrophilia

- Neutropenia

Question 21

• ↑ Eosinophils

- ↓ Eosinophils

Answer 21

• Eosinophilia

- Eosinopenia

Question 22

• ↑ Basophils

- ↓ Basophils

Answer 22

• Basophilia

- Basopenia

Question 23

• ↑ Platelets

- ↓ Platelets

Answer 23

• Thrombocytosis

- Thromocytopenia

Question 24

All cell types ( ↓ )

Answer 24

Pancytopenia