Drug Induced Renal Failure Flashcards

1
Q

Prerenal

A
  • Diuretics

- ACE inhibitors

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2
Q

Vasoconstriction

A
  • NSAIDs

- Cyclosporine

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3
Q

Crystalluria

A
  • Sulfonamides

- Acyclovir

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4
Q

Tubular Toxicity

A
  • Aminoglycosides

- Cisplatin

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5
Q

Endothelial Injury

A
  • Cocaine

- Oestrogen

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6
Q

Glomerularopathy

A
  • Penicillamine

- NSAIDs

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7
Q

Interstitial Nephritis

A
  • Antibiotics

- NSAIDs

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8
Q

T/F : Drugs bind covalently to proteins to form immunogens

A

True

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9
Q

Drug induced allergic reactions due to ( antibody ? )

A

Antibody ( Type I - III )

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10
Q

Drug induced allergic reaction can be cell mediated ?

A

Cell mediated ( Type IV )

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11
Q

What kind of reaction can penicillin cause ?

A

Anaphylactic shock

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12
Q

What kind of reaction can methyldopa cause ?

A

Anaemia

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13
Q

What kind of reaction can clozapine cause ?

A

Agranulocytosis

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14
Q

What kind of reaction can quinine cause

A

Thrombocytopenia

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15
Q

What do you call an ↑ in RBC

A

Erythrocytosis

Polycythemia

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16
Q

↓ in RBC ?

A

Anaemia

Erythroblastopenia

17
Q
  • ↑ in WBC

- ↓ in WBC

A
  • Leukocytosis

- Leukopenia

18
Q
  • ↑ in Lymphocytes

- ↓ in Lymphocytes

A
  • Lymphocytosis

- Lymphocytopenia

19
Q
  • ↑ Granulocytes

- ↓ Granulocytes

A
  • Granulocytosis

- Granulocytopenia / Agranulocytosis

20
Q
  • ↑ Neutrophils

- ↓ Neutrophils

A
  • Neutrophilia

- Neutropenia

21
Q
  • ↑ Eosinophils

- ↓ Eosinophils

A
  • Eosinophilia

- Eosinopenia

22
Q
  • ↑ Basophils

- ↓ Basophils

A
  • Basophilia

- Basopenia

23
Q
  • ↑ Platelets

- ↓ Platelets

A
  • Thrombocytosis

- Thromocytopenia

24
Q

All cell types ( ↓ )

A

Pancytopenia