Major Noncommunicable Diseases Flashcards
NCDs
- Dses of the heart and vascular system (1/3 of deaths in PH) 30.2%
other NCD
- malignant neoplasm
- COPD
- DM
What are the 4 major NCDs in the PH?
CVD
Cancers
COPD
DM
NCDs are linked to common preventable risk factors to lifestyle s/a:
- tobacco use
- unhealthy diet
- lack of physic activity
- alcohol use
What are the 6 prevalent risk factors to NCD? FILIPINOS
- smoking
- physical inactivity
- hypertension
- hypercholesterolemia
- overweight
- obesity
What is defined as single visit systolic BP of >140mmHg, or diastolic BP of >90mmHg
Hypertension
Calculation of BMI
Divide wt in kg by ht in meters squared
BMI of 23-24.9
Overweight
BMI of >/= 25
Obese
BMI (WHO)
Underwt: <18.5
Normal: 18.5-24.9
Overwt: 25-29.9
Obese: >/=30
BMI (Asia-Pacific)
Underwt: <18.5
Normal: 18.5-22.9
Overwt: 23-24.9
Obese: >/=25
Elevated CHOL in the bld is dt abnormalities in lvls of what?
Lipoproteins - particles that carry CHOL in the bloodstream
Hypercholesterolemia may be related to:
- diet
- genetic factors (LDL receptor mutations in familial hypercholesterolemia)
- presence of dses (diabetes and underachieved thyroid)
It refers to the body’s inability to produce enough insulin, or bcs cells do not respond to the insulin that is produced
DM
Hyperglycemia is based on FBS that is =/>
> /= 126mg/dL
It is associated with mental disorders, suicide, cancers, other NCDs s/a cirrhosis, intentional and unintentional injuries.
Alcohol intake
Studies shown that mental health is linked with NCDs, example:
Depression and heart dse
Stroke
Diabetes
Asthma
Cancer
Tobacco and alcohol use may influence onset, course, and outcomes of
Heart dse
Most commonly reported symptoms of mental illness in the PH include 2 important mental health illness closely linked w noncommunicable dse, specifically
Excessive sadness and no ctrl over use of cigarettes and alcohol
Globalization, urbanization, and population ageing are global scenarios that leads to common risk factors. What are the common risk factors?
- unhealthy diet
- physical inactivity
- tobacco
- alcohol use
The COMMON risk factors give rise to INTERMEDIATE risk factors such as:
- high blood pressure
- elevated blood glucose
- abnormal lipid profiles
- overweight/obesity
The INTERMEDIATE risk factors predispose individuals to the “fatal four” which are
Cardiovascular dse
Cancer
Chronic respiratory disease
Diabetes mellitus
Underlying determinants
GUP
Globalization
Urbanization
Population Ageing
Common risk factors
PUTAH
Physical inactivity
Unhealthy diet
Tobacco and alcohol use
Age (nonmodifiable)
Hereditary (nonmodifiable)
Intermediate risk factors
ROAR
Raised blood sugar
Overweight/obesity
Abnormal blood lipids
Raised BP
Main chronic diseases
Heart disease
Cancer
Stroke
Chronic respiratory diseases
Diabetes
Risk factors that lead to the 4 major NCDs namely Cardiovascular dse (coronary arty dse, hypertension, stroke), Diabetes Mellitus, Cancers, and Chronic Respiratory dses (COPD, asthma).
Smoking, diet/nutrition, physical inactivity, obesity
Risk factors that lead to the 3 major NCDs namely Cardiovascular dse (coronary arty dse, hypertension, stroke), Diabetes Mellitus, and Cancers.
Raised blood sugar and abnormal blood lipids
Risk factors that lead to the 2 major NCDs namely Cardiovascular dse (coronary arty dse, hypertension, stroke) and Cancers
Alcohol
Risk factors that lead to the 2 major NCDs namely Cardiovascular dse (coronary arty dse, hypertension, stroke), and Diabetes Mellitus
Raised blood pressure
Cardiovascular dses include dses of the heart and blood vessels such as
Coronary artery dse
Hypertension
Stroke
What is a heart dse c/b impaired coronary blood flow?
Coronary Artery Dse (AKA ischemic heart dse)
This occurs when there is a decreased oxygen supplied to the heart muscle.
Chest pain (Angina)
What can cause MI, arrhythmias, heart failure, and sudden death?
Coronary artery disease
What is the most common cause of CAD - coronary artery disease?
Atherosclerosis
This is the thickening of the inside walls of arteries d/t deposition of a fat-like substance.
Atherosclerosis
What happens when there is thickening of the arteries?
There will be a narrow space in which blood flows, thereby decreasing or cut-off completely the supply of oxygen and nutrients to the heart.
Atherosclerosis usually occurs when a person has high levels of _______ in the blood.
Cholesterol - the higher lvl of bld CHOL, he higher the chance for it to be deposited onto the artery walls
In this disease, atherosclerosis is accelerated. Often resulting in CAD, MI, and stroke.
Diabetes mellitus
Risk factors for CAD
Elevated blood cholesterol
Smoking
Hypertension
Obesity
Physical inactivity
What is the effect of high saturated fat intake, obesity, sedentary lifestyle, smoking, androgens, and certain drugs?
Increased LDL
What facilitates reverse transport of cholesterol to the liver where it may be excreted and therefore prevent atherosclerosis?
HDL - protective factor against CAD
HDL is decreased in
Smoking
Obesity
Diabetes mellitus
What increases HDL levels?
Regular exercise
Moderate alcohol consumption
HPN and smoking double your chance of developing what?
Heart dse if you have high cholesterol
Obesity and being overweight increase the chance of developing what?
High blood cholesterol
High BP
Physical inactivity increases the risk of what?
Heart attack
Having diabetes even without other risk factors may lead to
Heart dse
Because diabetes is an independent risk factor for CAD; diabetes accelerates atherosclerosis development
What is a sustained elevation in mean arterial pressure?
Hypertension
HPN is an intermediate risk factor for the development of what?
CVD like coronary heart dse or stroke
Primary HPN is attributed to
Atherosclerosis
Secondary HPN is usually the result of some other primary dses leading to HPN such as
Renal disease
What are the aging processes that increase BP?
Stiffening of arteries
Decreased baroreceptor sensitivity
Increased peripheral resistance
Decreased renal blood flo
Inability to talk
Aphasia
What is the most common cause of stroke?
Atherosclerosis
This usually occurs in atherosclerotic blood vessels, this is usually seen in older and may occur in a person at rest.
Thrombotic stroke
What is caused by a moving blood clot usually from a thrombus in the left in the left heart that becomes lodged in a small artery thru which it can’t pass.
Embolic stroke - sudden onset
Most fatal type of stroke
Hemorrhagic stroke
What is d/t intracerebral hemorrhage or rupture of intracerebral blood vessels?
Hemorrhagic stroke
What is the most common predisposing factor of hemorrhagic stroke?
Hypertension
Other causes of hemorrhage
Aneurysms
Trauma
Erosion of vessels by tumors
Arteriovenous malformations
Blood disorders
Sudden occurrence, active person
Hemorrhagic stroke
Diabetes is also an independent risk factor for
Stroke, also strongly correlated w high BP
What is a rapid, uncoordinated beating of the heart’s upper chambers, that also raises risk for stroke?
Atrial fibrillation
IV drug abuse carries high risk of stroke from
Cerebral emboli
What are chemicals found in cigar, industrial agents, or smoked food? Are also produced from animal fat in broiling meats.
Polycyclic hydrocarbons
Found in peanuts and peanut butter
Aflatoxin
Chemical produced when meat and fish are charcoal broiled or smoked, tinapa
Benzopyrene
Produced when food is fried in fat and reused repeatedly
Benzopyrene
Used as preservatives in food like tocino, longganisa, bacon, and hotdog
Nitrosamines
Inhibits nitrosamine formation
Vitamin C in stomach
What is caused by an interaction between 2 factors: genetics and lifestyle/environmental factors (obesity, nutrition, lack of exercise)?
DM
Characterized by absolute lack of insulin due to damaged pancreas, prone to develop ketosis, and dependent on insulin injections.
Type I IDDM
What are other causes of IDDM?
Genetic, environment, or acquired d/t viruses (e.g. mumps, congenital rubella) and chemical toxins (e.g. nitrosamines)
More common, more preventable because it is associated with obesity and diet
Type II NIDDM
What is characterized by fasting hyperglycemia despite availability of insulin? Possible causes include impaired insulin secretion, peripheral insulin resistance and increased hepatic glucose production.
Type II NIDDM
older
overwt
Risk factor for diabetes (CHOL & BMI)
HDL <35mg/dL (0.90mmol/L)
and/or
TAGs >250mg/dL (2.82 mmol/L)
Overweight (23) and obese (>30kg/m2)
Elevated CO2 in blood
Hypercapnea
This causes an associated increase in airway hyper-responsiveness that leads to recurrent episodes of wheezing, breathlessness, chest tightness and cough, particularly at night or early morning.
Chronic inflammation
What is usually d/t chronic bronchitis and emphysema (both are due to smoking)?
COPD
Key areas for primary prevention of the major NCDs
- Promote proper nutrition
- Encourage more physical activity and exercise
- Promote a smoke-free individuals and environment
- Discourage excessive alcohol drinking
- Manage stress efectively
- Regular health check up for early diagnosis and prompt tx
West Pacific Regional Plan 8 key principles
- People-centered health care
- Cultur relevance
- Focused on reducing inequities
- Encompassing entire care continuum
- Involving whole society
- Integral to health systems strengthening
- Consistent with global action plan
- Flexibility thru a phased approach