CN2 Cestodes Flashcards

1
Q

In T. saginata, can man serve as an intermediate host?

A

No, defibitive host only

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2
Q

T. saginata adult worms inhabit in the jejunum and may live for how many yrs?

A

25 yrs

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3
Q

How long is taenia saginata?

A

4-10 m in length, we have 1,000 up to 4,000 proglottids

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4
Q

How long is the cuboidal scolex of taenia saginata?

A

1-2mm in diameter, and have 4 prominent acetabula

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5
Q

It is devoid of hooks or a rostellum and is attached to a short neck from which a chain of immature and gravid proglottid develop

A

Scolex of taenia saginata

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6
Q

Gravid proglottid are longer than wide in taenia saginata and the uterus is distended with ova and has

A

15 to 20 lateral branches

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7
Q

Spherical
30 to 45 micrometers
Brownish
Thick embryophore

A

Taenia saginata eggs

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8
Q

What is inside the egg shell of taenia saginata?

A

Oncosphere or embryo provided with three pairs of hooklets

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9
Q

In taenia solium, can serve as an intermediate host?

A

Yes, both definitive and intermediate host

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10
Q

Where does the taenia solium adult worm inhabit?

A

Upper part of the small intestine

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11
Q

How long is taenia solium?

A

2 to 4 m in length and may have 800 to 1,000 proglottids

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12
Q

Have 4 acetabula wc is smaller (1mm) and more spherical

Carries a cushion like rostellum with a double crown of 25-30 large and small hooks

A

Scolex of taenia solium

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13
Q

It has accessory ovarian lobe
No vaginal sphincter
Smaller number of follicular cells (100 to 200)
Gravid proglottid contains 7-15 lateral braches

A

Taenia solium

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14
Q

30-45 um

Thick brown striated embryophore surrounding a hexacanth embryo

A

T. solium

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15
Q

Which infection is more common in the Philippines?

A

Taenia saginata

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16
Q

In the life cycle of taenia saginata, upon ingestion of the eggs by the cattle, what is released?

A

Oncosphere

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17
Q

T. saginata: Where does the oncosphere actively penetrate and then enters a venule from which it is carried to different parts of the body?

A

Intestinal mucosa

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18
Q

T. saginata: once it enters a muscle fiber and it develops into an infective stage in 2 mos called

A

Cysticercus bovis

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19
Q

T. saginata: It is a ovoidal, milky white, about 10 mm in diameter and a single scolex invaginated into a fluid filled bladder

A

Cysticercus

20
Q

The larva is digested out of the meat and the scolex evaginated to attach to the mucosa of the SI where it will become mature in how many weeks?

(T. saginata)

A

12 weeks

21
Q

In T. solium the oncosphere penetrates the intestinal mucosa to encysts in muscles as

A

Cysticercus cellulosae

22
Q

Oval, translucent with opaque invaginated scolex with four suckers and a circlet of hooks

A

Mature cysticercus

23
Q

In taenia saginata, passage of proglottid causes:

A

Mild irritation at the site of attachment

24
Q

Nonspecific symptoms such as epigastric pain, vague discomfort, hunger pangs, weakness, weight loss, loss of appetite and pruritus ani

A

T. saginata symptoms

25
Q

Rarely tangled problems may result in

A

Intestinal obstruction

26
Q

What is the most serious manifestation of taenia solium which is considered one of the most serious zoonotic disease worldwide?

A

Neurocysticercosis

27
Q

What are observed when cysts are in the cortex?

A

Seizures

28
Q

The subarachnoid form may lead to aggressive form called

A

Racemous cysticercosis

29
Q

In the eyes, cysticerci may float freely where?

A

Vitreous humor

30
Q

Vision is usually affected due to

A

Chorioretinitis and vasculitis

31
Q

What can D. latum result in?

A

Hyperchromic, megaloblastic anemia with thrombocytopenia and leukopenia

32
Q

What is the drug of choice for T. saginata infxns?

A

Praziquantel 5-10mg/kg as single dose

33
Q

What is the criteria for cure in T. saginata?

A

1) recovery of scolex

2) negative stool exam 3 mos after tx

34
Q

What is the drug of choice for T. solium infxns in INTESTINAL?

A

Praziquantel 5-10mg/kg

Niclosamide (not locally available)

35
Q

What is the drug of choice for T. solium infxns in CYSTICERCOSIS - multiple parenchymal cystic lesions?

A
  • Praziquantel at a dose of 50-75 mg/kg divided in 3 doses for 30 days
  • Albendazole at a dose of 400mg twice daily for 8-30 days

Steroids are then given 4 hrs after last dose

  • 80mg Prednisone
  • 10mg IM Dexamethasone
36
Q

Parenchymal forms presenting as cysticercotic encephalitis or those with massive parasitic infection are given high-dose corticosteroid therapy and mannitol in cases of

A

Increased intracranial pressure

37
Q

In what temperature can kill the cysticerci?

A

Freeze at -20°C for 10 days

38
Q

Surgical removal of lesions

Albendazole therap: 10-15mg/kg/day for 8 days

A

Subarachnoid cysticercosis

39
Q

Surgical remobal of cyst

A

Ventricular cysticercosis

40
Q

Treated surgically before Praziquantel or Albendazole bcs ocular inflam can’t be ctrlled by steroids

A

Ocular cysticercosis

41
Q

What will you do to symptomatic cysts outside CNS?

A

Surgical removal

42
Q

Common symptoms for D. latum

A

Nervous disturbances
Digestive disorders
Abdominal discomfort
Wt loss
Weak
Anemia

43
Q

Vomiting
Colicky abdominal pain
Murphy’s sign
Cholangiopancreatography (cholecystitis)

A

T. saginata

44
Q

Larval maturation of T. saginata in small intestine

A

12 weeks

45
Q

Drug that may cause blindness in px w ocular cysticercosis

A

Praziquantel