Magnesium

Question 1

What is the function of Magnesium?

Answer 1

Facilitates Sodium/Potassium ATPase activity in cell membranes
structural role in bone formation
important role in PTH synthesis and release
Roles in cell membrane functions: Nerve conduction, Calcium channel activity, and Phosphorus transport

Question 2

Causes of Hypomagnesemia?

Answer 2

Lost through the GI trct, kidney, and skin in horses
Fluid diuresis
renal disease
Hypercalcemia will inhibit magnesium reabsorption
Dietary deficiency in ruminants
Grass tetany
Milk tetany

Question 3

What disorders are associated with Hypomagnesemia?

Answer 3

Diabetes Mellitus
Hypercalcemia
Hyperaldosteronism
Third space syndromes

Question 4

Clinical signs with hypomagnesemia?

Answer 4

Hyperexcitability 
Tremors
Fasciculation 
Ataxia
Frank tetany 
Cardiac arrythmias
possible arrest 
Coronary artery spasms in humans

Question 5

Causes of Hypermagnesemia?

Answer 5

Impaired Renal function
Magnesium containing laxatives or antacids
decreased GFR

Question 6

Clinical signs of Hypermagnesemia?

Answer 6

Paresis
paralysis
heart dysfunction
GI upset