Blood Typing and Crossmatching Flashcards
Do dogs have isoantibodies against other blood groups?
No
Do dogs have isoantibodies against other blood groups?
No
What antigen do dalmations lack?
Dal antigen
What are the two feline blood groups?
AB group system
Mik system
What feline blood type is most common?
Type A
What breeds have feline type A?
DSH/DLH
Do feline type A have strong or weak antibodies against type B?
Weak
Do feline type B have strong or weak antibodies against Type A?
Strong
What breeds have feline type B?
British Breeds
What feline blood type is rare and found in purebred cats?
Type AB
What feline blood type is rare and found in purebred cats?
Type AB
Are single crossmatched whole blood transfusions well-tolerated in large animals?
Yes
How many blood systems do Equines have?
7
What two blood types are implicated in Equine Neonatal Isoerythrolysis?
Type Aa
Type Qa
Vaccinations of blood origin…
may sensitize a cow to foreign RBC antigens
can results in Neonatal isoerythrolysis in subsequent calves
Blood Typing
Identifies a specific RBC antigen
Uses a reagent called “antiserum”
Antiserum cross reacts with a specific RBC antigen
Is agglutination in blood typing a positive reaction?
YES!
Crossmatching
identifies antibodies against RBC antigens in the plasma of the recipient or donor
Crossmatching
identifies antibodies against RBC antigens in the plasma of the recipient or donor
Major Crossmatch =
Patient Serum + Donor RBCs
What does no agglutination in crossmatching mean?
No reaction!
Minor Crossmatch =
Patient RBCs + Donor Serum
If the crossmatch is positive do you transfuse?
NO!
What do you check for when macroscopically interpreting crossmatching?
Hemolysis
Agglutination
Horses have what two types of antibodies?
agglutinating
hemolytic
What are the goals of a transfusion?
Minimizes donor RBC destruction
Minimize recipient RBC destruction
What are the two types of transfusion reactions?
Immune-mediated
Non-immune mediated
What are the two types of transfusion reactions?
Immune-mediated
Non-immune mediated