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Farma > Macrolidos lincosamias y otros > Flashcards

Macrolidos lincosamias y otros Flashcards

1
Q

mecanismo de accion de los macrolidos

A

se unen a la subunidad 50s

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2
Q

los macrolidos son bacterioestaticos?

A

verdadero

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3
Q

se usan en px alergicos a penicilinas

A

macrolidos

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4
Q

MA de macrolidos

A

esimulan los receptores de motilina

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5
Q

como se debe administrar la eritromicina

A

oral en ayuno

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6
Q

se usa en tx de clamidia en embarazo

A

eritromicina

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7
Q

tx de neumonia y oftalmopatia en RN
neumonia por legionella
profilaxis de FIEBRE REUMATICA
TOSFERINA

A

eritromicina

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8
Q

EA de eritromicina

A

colestasis hepatica
arritmias
nauseas,vomito y diarrea

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9
Q

como se administra la claritromicina

A

con alimento

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10
Q

uso de la claritromicina

A

Elicobacter Pylori

1ra linea Mycobacterium avium

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11
Q

EA de Azitromicina

A

hepatotoxidad

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12
Q

como se administra la Azitromicina

A

se administra en ayunas reservorio en fibroblastos

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13
Q

es el macrolido de vida media mas larga

A

Azitromicina

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14
Q

se usa en Gonorrea
1 en legionella
URETRITIS NO GONOCOCCICA
MICOBACTERIUM AVIUM

A

Azitromicina

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15
Q

menciona un cetolido

A

Telitromicina

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16
Q

donde se concentra la telitromicina

A

Macrofagos

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17
Q

usos de telitromicina

A

Tx neumonia adquirida en la comunidad
faringitis estreptoccocica
bacteremia neumocitica

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18
Q

EA de telitromicina

A

Hepatotoxico

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19
Q

menciona las lincosamidas

A

Lincomicina Clindamicina

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20
Q

no cruzan la BHE

A

liconsamidas

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21
Q

uso de la lincomicina

A

tx neumococo

tx de huesos y articulaciones ya que penetra bien

22
Q

donde se concentra la lincomicina

A

prostata huso y liquido sinovial

23
Q

uso de la clindimicina

A

tx abscesos pulmonares

tx encefalitis por toxoplasma

24
Q

donde se acumula la clindamicina

A

PMN y macrofagos alveolares

25
Q

EA de clindamicina

A

colitis pseudomembranosa por c. dificile

sdsteven jhonson

26
Q

menciona las Polimixinas

A

B y E colistina

27
Q

MA de polimixinas

A

detergentes cationicos

28
Q

Tx DE POLIMIXINAS

A

otitis externa y ulceras corneales causadas por pseudomonas

29
Q

EA de polimixinas

A

nefrotoxicidad neurotoxicidad

30
Q

menciona los glucopeptidos triciclicos

A

vancomicina teicoplanina

31
Q

MA de la vancomicina

A

se une a D alanina y suprime la sintesis de pared celular

32
Q

la vancomicina es bactericida

A

verdadero

33
Q

uso d ela vancomicina

A

colitis seudomembranosa
SARM
mas gentamicina para endocarditis enterococica e alergicos a penicilina
infecciones de protesis valvulares cardiacas

34
Q

EA de vancomicina

A

sindrome hombre rojo

35
Q

que evita el EA de vancomicina

A

administracion lenta del medicamento mas esteroides

36
Q

menciona los lipopeptido ciclico

A

daptomicina
mupirocina
bacitracina

37
Q

MA de daptomicina

A

se une a membrana de bacterias perdida de potencial y muerte celular

38
Q

uso de daptomicina

A

infecciones cutaeas

ENDOCARDITIS DERECHA

39
Q

EA de daptomicina

A

aumento de la creatinin cinasa

40
Q

MA de mupiricina

A

suprime la sintesis bacteriana de proteinas al inhibir la isoleucil RNAt sintasa

41
Q

Administracion de la mupirocina

A

topico solamente

42
Q

uso de mupirocina

A

impetigo

tx nasal de S.Aureus

43
Q

menciona las Oxazolidiononas

A

linezolida esperizolide

44
Q

MA de linezolida

A

bloquea s50

45
Q

uso de la linezolida

A

intrahospitalario

46
Q

la linezolida es

A

bacteriostatico

47
Q

tx de linezolida

A

bacterias gramm positivas resistentes a todo

48
Q

EA de linezolida

A

trombocitopenia sd serotoninergico

49
Q

MA de quinupristina

A

se une a s50

50
Q

tx de infecciones por e facieum resistente a vancomicina

A

Quinupristina

Farma (19 decks)

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