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Farma > Hepatitis > Flashcards

Hepatitis Flashcards

1
Q

que interferones se usan Hepatitis

A

beta alfa en todas las celulas, gamma natural killer y linfocitos T

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2
Q

MA de los interferones

A

inhiben la 2 5 oligoadenilato sintasa

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3
Q

uso de interferones

A

condilomas acuminados
sarcoma de kaposi
hepatitis B y C

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4
Q

EA de interferones

A

Sindrome Pseudoripal
niños da alopecia
cambios en la personalidad
miolosupresion

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5
Q

Analogo de nuclosido purinico

A

Ribavirina

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6
Q

MA de la ribavirina

A

inhibe la mARN viral

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7
Q

uso de la ribavirina

A

infeccion cronica de hepatitis c

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8
Q

tambien es sada en virus sincitial respiratorio influenza y paraninfluenza

A

Ribavirina

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9
Q

EA de la ribavirina

A

anemia reversible y teratogenico

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10
Q

CI de ribavirina

A

embarazadas categoria X

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11
Q

es analogo de adenosina

A

Adefovir

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12
Q

MA de adefovir

A

se une a DNA polimerasa y transcriptasa inversa

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13
Q

uso de adefovir

A

hepatitis cronica con HBeAG

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14
Q

EA adefovir

A

Hiperazoemia e hipofosfatemia

astenia dolor abdominal nefrotoxicidad acidosis glucosuria y proteinuria C en embarazo

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15
Q

son frmacos anti VHB Y VIH

A

Tenofovir Lamivudina telvivudina Emtrictabina

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16
Q

MA de entecavir

A

inhibe la polimerasa de ADN

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17
Q

uso de Entecacir

A

hepatitis cronica con replicacion activa

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18
Q

uso de tenofovir

A

VIH y HBV

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19
Q

EA de tenofovir

A

flatulencia y sd de fanconi

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20
Q

MA de Telbivudina

A

inhibe ADN polimerasa analogo de timidina

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21
Q

uso de Telbivudina

A

hepatitis B cronica

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22
Q

EA de telvibudina

A

Miopia

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23
Q

uso de Lamivudina

A

VIH y hepatitis B

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24
Q

MA de Lamivudina

A

inhibe ADN polimerasa y transriptasa reversa

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25
Q

quien disminuye l riesgo de carcinoma hepatocelular

A

Lamivudina

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26
Q

USA para molusco contagioso y condilomas acuminados

A

Imiquimod

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27
Q

es numero uno contra Papilomas VPH

A

imiquimod

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28
Q

esquema base VIH

A

1 NRTI 1 NNRTI INH DE PROTEASA

29
Q

esquema preferido VIH

A

2 NRTI 1NNRTI

30
Q

combinacion usada en neonatos

A

Zidovudina Nevirapina

31
Q

combinaciones en embarazadas

A

Zidobudina Lamivudina Lopinavir

32
Q

CI en embarazo

A

Saquinavir Ritonavir Delavirdina

33
Q

primera eleccion VIH positivos

A

tenofovir efavirenz emtricitabina

34
Q

meniona NRTI

A

Zalcitabina Zidobudina Estavudina Didanosina Lamivudina AAbacavir
Tenofovir Emtricitabina

35
Q

primera eleccion en trabajadores sanitarios y prevencion madre feto

A

Zidovudina

36
Q

la zidovudina cruza BHE y leche materna

37
Q

uso de Zidovudina

38
Q

se usa de profilaxis en contacto

A

Zidovudina

39
Q

EA neuropatia periferica
lipodistrofia
esteatosis hepatica

A

Estavudina

40
Q

EA neuropatia

PANCREATITIS y se deve dar con antiacidos

A

Didanosina

41
Q

uso de Lamivudina

42
Q

USO DE Abacavir

43
Q

EA de Abacavir

A

Hipersensibilidad

44
Q

EA de Emtricitabina

A

Neuropatia periferica

Pancreatitis

45
Q

Menciona NNRTI

A

Etravirina Nevirapina
Delaviridina
Efavirenz

46
Q

MA de NNRTI

A

se unen a P66 Inhiben la transcriptasa inversa

47
Q

no se deve mezclar con oros

A

Etravirina

48
Q

TX en lactantes y menores 15 dias

A

Nevirapina

49
Q

vida media de Efavirenz

50
Q

como se administra Efavirenz

A

estomago vacio

51
Q

EA de efavirenz

A

teratogeno primeras 8 semanas mareo disforia y sueños vividos

52
Q

EA de Nevirapina

A

exantema sd stevens Johnson

53
Q

menciona inhibidores de proteasa

A

Saquinavir Ritonavir Fosamprenavir
Lopinavir
Atazanavir Darunavir Indinavir Tripanavir Nelfinavir

54
Q

uso de los inhibidores de proteasa

55
Q

MA de inhibidores de proteasa

A

inhiben espartil proteasa viral

56
Q

EA de inhibidores de proteasa

A

resistencia insulina y lipodistrofia

57
Q

siempre se da con ritonavir

A

Saquinavir

58
Q

es un reforzador farmaceutico, disminuye el metabolismo de los demas farmacos excepto Nelfinavi

59
Q

se usa en pacientes pediatricos sin tratamiento previo

A

Fosamprenavir

60
Q

se puede dar en embrazo

61
Q

es el unico que causa reduccion de colesterol y trigliceridos

A

atazanavir y darunavir

62
Q

EA de cristaluria

63
Q

aumenta el colesterol y trigliceridos

A

Tipranavir

64
Q

induce su propio metabolismo y se da en embarazadas

A

Nelfinavir

65
Q

menciona los inhibidores de entrada

A

Maraviroc Enfuvirtida

66
Q

es un agonista de GP 120 con CCR5

67
Q

antagonista de gp41 e infeccion de celulas CD4

A

Enfuvirtida

68
Q

menciona inhividor de integrasa

A

reltgravir

69
Q

evitita la integracion del ADN al hospedador

A

Reltagravir

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