M31: Endocrine System Overview Flashcards
name the 5 endocrine only glands
- pituitary gland
- pineal gland
- parathyroid glands
- thyroid gland
- adrenal glands
“master gland” of the body
pituitary gland
“master gland”
pituitary gland
pineal gland location + function
part of epithalamus
- secretes melatonin (helps with circadian rhytm)
thyroid gland location + function
surrounds trachea
- regulate metabolism
parathyroid glands location + function
back of thyroid gland
- regulate ion levels in blood, specifically Ca2+
adrenal gland location + function
top of kidneys
- release hormones apart of ANS
- releases ALDOSTERONE (regulates ion concentration in kidney tubules)
endocrine vs exocrine glands
EXOCRINE
- secrete products into ducts that empty into body cavities or surfaces
ENDOCRINE
- secrete products (hormones) into interstitial bloodstream
name other organs that secrete hormones as a second function
- hypothalamus
- thymus
- stomach, liver, pancreas, kidneys, small intestine
- ovaries, testes, placenta
- heart
- skin
- adipose tissue
4 general functions of hormones
- Help regulate
- Interstitial fluid composition
- metabolism
- blood glucose
- contraction of cardiac and smooth muscle
- immune functions - Growth and development
- Regulate reproductive systems
- Circadian rhythms
Target organs for specific hormones are determined by…
the specific type of receptor on the target tissue
down-regulation and up-regulation of hormones
DOWN: excess hormone causes a decrease in # of receptors -> decreased sensitivity
UP: deficiency of hormone causes an increase in the # of receptors -> increased sensitivity
circulating vs local hormones
CIRCULATING
- act on distant targets
- travel in blood
LOCAL
- PARACRINES: act on neighbouring cells
- AUTOCRINES: act on same cell (or cells like it) that secrete them
where do water soluble vs lipid soluble hormones bind onto cells?
water - cell surface
lipid - inside the cell
how may cells respond to hormone binding?
(5 ways)
- synthesis of new molecules
- changing permeability of cell membrane
- transport substance in/out of cell
- altering metabolic actions
- causing contraction of smooth muscle