M16: Digestive System - Salivary Glands, Swallowing & Stomach Flashcards

1
Q

two types of glands that secrete saliva into oral cavity

A
  1. Glands within mucous membranes of oral cavity
    - LABIAL (lips)
    - BUCCAL (cheeks)
    - PALATAL (palate)
    - LINGUAL (tongue)
  2. Glands outside the mouth (empty their contents into ducts which deliver saliva into the oral cavity)
    3 pairs
    - PARATOID
    - SUBMANDIBULAR
    - SUBLINGUAL
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2
Q

parotid glands structure + function

A
  • largest external salivary glands
  • dump into area of 2nd molar
  • inferior and anterior to ear
  • produce most watery saliva (with lots of salivary amylase)
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3
Q

submandibular glands structure + function

A
  • external salivary gland
  • beneath base of tongue
  • ducts beside lingual frenulum
  • less liquid saliva because more mucous
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4
Q

sublingual glands structure + function

A
  • external salivary gland
  • superior to sublingual, floor of mouth
  • series of ducts that reach floor of mouth
  • thick saliva with little salivary amylase
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5
Q

saliva structure and function

A

Structure
- 99.5% water
- 0.5% solutes (mostly ions), LYSOZYME (antibacterial agent), IgA (immune function, attacks microbes)

Function
- dissolves food for tasting
- mucous - lubricates food
- CI- activates salivary amylase
- HCO3- (bicarbonate) buffer acidic foods

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6
Q

how do we increase salivation?

A
  • parasympathetic stimulation
  • Facial (VII) and Glossopharyngeal (IX) nerve stimulate salivary glands
  • cerebral cortex (sensory stimulation like sight/smell)
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7
Q

how do we reduce salivation

A

sympathetic stimulation

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8
Q

mechanical vs chemical digestion in mouth

A

MECHANICAL
- breaks food into pieces
- mixes with saliva to form a BOLUS

CHEMICAL
Salivary amylase
- begins starch digestion (polysaccharides to disaccharides)
- when swallowed, stomach acids deactivates it
Lingual lipase
- secreted by glands in tongue
- activated by stomach acids
- begins breakdown of triglycerides into fatty acids and glycerol

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9
Q

order of structures that bolus moves through

A
  • mouth: bolus formed from chewing
  • pharynx: movement into pharynx begins deglutition (facilitated by saliva and mucous)
  • esophagus: secretes mucous
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10
Q

histology of esophagus

A

Mucosa
- stratified sqamous
- terminal end has mucous glands

Submucosa
- mucous glands

Muscularis
- upper 1/3 is skeletal muscle
- middle is mixed
- lower 1/3 is smooth muscle
- UPPER ESOPHAGEAL SPHINCTER (skeletal)
- LOWER ESOPHAGEAL SPHINCTER (smooth)

ADVENTITIA (outer layer)
- areolar connective tissue

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10
Q

deglutition

A

swallowing

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11
Q

3 stages of swallowing (deglutition)

A
  1. VOLUNTARY STAGE
    - bolus pushed into oropharynx
  2. PHARYNGEAL STAGE (involuntary)
    - sensory nerves send signals to deglutition centre in brainstem (medulla oblongata)
    - soft palate lifted to close nasopharynx
    larynx lifted up and epiglottis bent to cover glottis
  3. ESOPHAGEAL STAGE
    - bolus enters esophagus
    - upper sphincter relaxes when larynx is lifted
    peristalsis pushes food down
    - circular fibres contract behind bolus
    - longitudinal fibres shorten distance in front of bolus
    -lower sphincter relaxes as food approaches
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12
Q

duodenum structure function

A

first portion of small intestine that attaches to stomach

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13
Q

curves in shape of stomach are called…

A

greater curvature
lesser curvature

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14
Q

4 main regions in stomach

A

CARDIA
- closest to esophagus
FUNDUS
- superior to cardia, forms pocket at top of stomach
BODY
- main and largest part
PYLORIC PART:
- 3 parts, leads to SI
1. PYLORIC ANTRUM
2. PYLORIC CANAL
3. PYLORUS (into SI)
- PYLORIC SPHINCTER: controls movement from stomach into SI

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15
Q

ridges in stomach are called…

A

rugae
- found in mucosa layer
- allow for expansion

16
Q

function of fundus

A
  • holds bolus after it passes through cardia
  • doesn’t come in contact with gastric juices (salivary amylase continues to work)
17
Q

outermost layer of stomach

A

SEROSA
(visceral peritoneum)

18
Q

why is muscularis layer in stomach different?

A

3 layers of muscle
superficial to deep
- longitudinal
- circular
- oblique

19
Q

4 functions of the stomach

A
  1. mixes saliva, food and gastric juices to form CHYME
  2. serves as reservoir for food before release into SI
  3. secretes gastric juices containing…
    - HCL: kills bacteria
    - PEPSIN: begins pr- digestion
    - INTRINSIC FACTOR: B12
    absorption
    - GASTRIC LIPASE: digestion of
    triglycerides
  4. secretes GASTRIN into blood: signalling digestive processes in GI tract
20
Q

gastric glands

A
  • columns of secretetory cells near the base of extensions of the lamina propria
  • form narrow chanels: GASTRIC PITS

cells
- SURFACE MUCOUS CELLS
- MUCOUS NECK CELLS
produce alkaline mucous to protect outer stomach layers from stomach acid
- PARIETAL CELLS: release HCL and intrinsic factor
- CHIEF CELLS: release enzymes

entero-endocrine cell
- G CELL: secretes hormone into blood that helps controlm digestive processes

21
Q

intrinsic factor function

A

helps with absorption of vitamin B12

22
Q

function of pepsinogen

A

helps begin breakdown of proteins

23
Q

function of gastric lipase

A

breakdown of triglycerides (fat)