M2: Stem Cells & Differentiation Flashcards
2.1.6 Stem Cells & Differentiation: Cells
What are Cells?
Carry out all necessary functions for life
2.1.6 Stem Cells & Differentiation: Cells
What are Tissues?
Collection of differentiated similar cells that have specific functions
2.1.6 Stem Cells & Differentiation: Cells
What are the Main Types of Animal Tissues?
- Nervous tissue
- Epithelial tissues
- Muscle tissues
- Connective tissue
2.1.6 Stem Cells & Differentiation: Cells
What are the Main Types of Plant Tissues?
- Epidermis tissues
- Vascular tissues
2.1.6 Stem Cells & Differentiation: Cells
What are Organs?
Collection of tissues that are adapted to carry out a particular function
2.1.6 Stem Cells & Differentiation: Cells
What’s an Organ System?
Number of organs used to carry out the major functions of an organism
2.1.6 Stem Cells & Differentiation: Stem Cells
What are Stem Cells?
Unspecialised cells
2.1.6 Stem Cells & Differentiation: Stem Cells
What are Unspecialised Cells?
Cells that can develop into diff types of cells
2.1.6 Stem Cells & Differentiation: Stem Cells
What’s the use of Stem Cells?
Source of new cells for:
* Growth
* Development
* Tissue repair
2.1.6 Stem Cells & Differentiation: Stem Cells
What’s the function of Stem Cells?
Can undergo cell division over & over again to become specialised
2.1.6 Stem Cells & Differentiation: Stem Cells
What happens when a Stem Cell has become Specialised?
They lose the ability to divide , entering G0 phase of the cell cycle
2.1.6 Stem Cells & Differentiation: Stem Cells
Why’s the Activity of Stem Cells Controlled?
If they don’t divide fast enough
↳ tissues aren’t efficiently replaced → causes ageing
2.1.6 Stem Cells & Differentiation: Stem Cells
What occurs when the Activity of Stem Cells is Uncontrolled?
Uncontrolled division forming masses of cells (tumours)
↳ lead to development of cancer
2.1.6 Stem Cells & Differentiation: Stem Cells Potency
What’s meant by Potency?
Stem cell’s ability to differentiate into diff types of cells
Greater the number of cells it can differentiate to = more potent
2.1.6 Stem Cells & Differentiation: Stem Cells Potency
What are Totipotent Cells?
Stem cells that can differentiate into any type of cell
2.1.6 Stem Cells & Differentiation: Stem Cells Potency
What are Examples of Totipotent Cells?
- Fertilised egg
- Zygote
- 8 or 16 cells from 1st few mitotic divisions
Can all become an organism & can differentiate into extra-embryonic tissues
↳ amnion & umbilicus
- Meristem (where growth takes place in a plant)
↳ can become xylem vessels & phloem sieve tubes
2.1.6 Stem Cells & Differentiation: Stem Cells Potency
What are Pluripotent Cells?
Stem cells that can form into all tissue types but not whole organisms
2.1.6 Stem Cells & Differentiation: Stem Cells Potency
Where are Pluripotent Cells found?
In any early embryos
↳ origin of diff types of tissues within an organism
2.1.6 Stem Cells & Differentiation: Stem Cells Potency
What are Multipotent Cells?
Stem cells that can only form a range of cells within a certain type of tissues
2.1.6 Stem Cells & Differentiation: Stem Cells Potency
What are Examples of Multipotent Cells?
Haematopoetic stem cells in bone marrow
↳ give rise to various types of blood cells
2.1.6 Stem Cells & Differentiation: DIfferentiation
What’s Differentiation?
Process by which a cell becomes specialised for its job
2.1.6 Stem Cells & Differentiation: DIfferentiation
What are Neutrophils?
Type of white blood cells
2.1.6 Stem Cells & Differentiation: DIfferentiation
What are Adaptations of Neutrophils?
- Flexible shape
↳ enables them to engulf foreign cells or pathogens - Many lysosomes (in cytoplasm)
↳ contains digestive enzymes to break down engulfed particles
2.1.6 Stem Cells & Differentiation: DIfferentiation
What are Erythrocytes?
Red blood cells