Lymphatics System II

Question 1

Largest lymphoid organ that filters the blood and removes old erythrocytes and platelets

Answer 1

Spleen

Question 2

The spleen is located in the left-posterior abdominal wall and originates from the ……

Answer 2

Mesoderm

Question 3

The spleen is covered by……

Answer 3

Dense connective tissue capsule

Question 4

Cords of cells (Cords of Billroth) and sinusoids (Venous Sinuses/Capillaries)

Answer 4

Red Pulp

Question 5

Thick accumulation of lymphocytes and lymphatic nodules (Malpighian corpuscles) occur in…

Answer 5

White Pulp

Question 6

……… facilitate the passage of blood vessels into the parenchyma from the capsule

Answer 6

Trabeculae

Question 7

Parenchyma that is penetrated by connective tissue septae

Answer 7

Trabeculae

Question 8

The splenic artery divides into branches, which run along the capsule and turns into ……. which branches off and runs through trabeculae and become ……

Answer 8

Capsular artery
Trabecular Arteries
(White Pulp)

Question 9

From the trabecular arteries, branches arise and run through the interior of parenchyma and are called ……

Answer 9

Central Arterioles

White Pulp

Question 10

Lymphocytes immediately surround this vessel and create the …..

Answer 10

PALS (peri arterial lymphatic sheath)

Question 11

Central arterioles gives rise to several smaller vessels which ultimately end in venous sinuses (also called splenic sinuses)

Answer 11

Penicillar arterioles

Question 12

Zone filled with lymphocytes, along with APCs (antigen presenting cells and macrophages) and surrounded by B and T lymphocytes

Answer 12

Marginal Zone

In this area, the lymphocytes first come in contact with antigens

Question 13

Traps antigen from the circulation and present the antigen to the lymphocytes of the spleen

Answer 13

Marginal Zone of the Nodule

Question 14

Red pulp is a dense network of ……….. erythrocytes, ……………., macrophages and plasma cells in between the splenic cords are the venous sinuses

Answer 14

Reticular FIbers

Lymphocytes

Question 15

Function s of Red Pulp:

Answer 15

filtration of antigens & senile and abnormal erythrocytes and platelets from the blood

Question 16

Splenic sinusoids (capillary) are lined by elongated endothelial cells and are supported by ……

Answer 16

incomplete basal lamina of reticular fibers

Question 17

…….. remove damaged or effete erythrocytes from circulation

Answer 17

Macrophages

Question 18

Located at the back of the oral cavity, in the tongue and pharynx that process antigens that enter the body through oral cavity and nasal passage

Answer 18

Tonsils

Question 19

Palatine tonsils:

Answer 19

Two tonsils located on either side of the oral cavity

Question 20

………… contain desquamated epithelial cells, live and dead lymphocytes and bacteria

Answer 20

Deep Tonsillar Crypts

Question 21

……… tonsil is located in posterior pharygeal wall (nasopharynx). When enlarged due to inflammation referred to as Adenoids

Answer 21

Pharyngeal tonsil

Question 22

……tonsil located at posterior aspect of tongue and is associated with shallow crypts and mucus glands

Answer 22

Lingual tonsils

Question 23

Lymph node enlargement
Follicular hyperplasia
Increase in number & size of cortical lymphoid follicles
Humoral response

Answer 23

Lymphadenopathy

Question 24

Expansion of paracortical zone caused by viral infection

Answer 24

Paracortical hyperplasia

Question 25

Medullary sinuses are extremely prominent- draining necrotic tumor

Answer 25

Sinus hyperplasia

Question 26

Lymph node’s main function is to ………

Answer 26

Filter Lymph

Question 27

……. invade into lymphatic channels draining
the primary tumor and so gain access to the
regional lymph nodes

Answer 27

Cancer Cells

Question 28

Malignant cells enter the ,,,,,, of the lymph node and may settle at this site where they could proliferate to form a secondary tumor mass.

Answer 28

Subcapsular sinus

SS