Lymphatics Flashcards
What are the 4 functions of the lymphatic system?
- Tissue drainage
- Return of plasma & proteins that leak out
- Carries absorbed fat from the gut
- Immunity
Why does the lymphatic system need to drain tissues?
High pressure causes fluid to leak from the capillary bed
Some is taken back in by venules but much needs to be drained.
Why does the Lymp. System need to return plasma & proteins?
Plasma and its proteins leak out the capilaries as well but cant be reabsorbed by venules so have to be returened to the venous system via the lymph.
How is the lymphatic system involved in immunity?
Lymph goes via lymph nodes which contain many antibodies & lymphocytes.
Why can lymphatic vessels absorb proteins & large molecules that blood cant?
Lymphatic vessels have no basement membrane
Examples of lymphatic tissues
Spleen
Thymus
Marrow
Tonsils
Lymph nodes
What makes up Lymph?
The fluid & plasma proteins int he vessels
Gains lymphocytes when passing through capillaires & fat when through small intestine
What causes Lymph to flow?
Pressure, gravity and muscle contraction
How is lymph flow kept unidirectional?
Valves
How is lymph flow altered in an infected space?
- Protein accumulates in infected space
- increased fluid flow to extracellular space
- Increases lymph flow through area
- More antigens from space reach nodes & immune resposne increases.
Where are lymph nodes found?
Isolated all over the body or in groups at the base of major arterial trunks
What is a lymph node?
Secondary Lymphoid tissue
A filter for lymph
When will a lymph node swell?
When the area it drains is infected
What do lymph nodes do?
Filter pathogens out of the lymph using white cells & plasma cells.
How do lymph nodes notify the body of pathogens?
By releasing antibodies and antigen-presenting cells into the lymph
what else do lymph nodes filter out?
Inert particles