lymphatic system and immune system Flashcards

1
Q

what direction does lymph flow

A

it always flows from the tissues back towards the heart

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2
Q

a clear, watery fluid that circulates throughout the body as part of the lymphatic system. it carries white blood cells, nutrients, and other substances.

A

lymph

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3
Q

a dilated sac-like structure at the base of the thoracic duct, located in the retroperitoneal space, which collects lymph from the intestines and lower body.

A

cisterna chyli

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4
Q

in the lymphatic system the spleen tissue

A

takes in blood and pumps out lymph

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5
Q

innate responses are

A

-surface barriers (1st line of defense)
-skin and mucous membrane
-internal defenses (2nd line of defense)
- phagocytes, inflammation, fever
-nonspecific

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6
Q

adaptive responses are

A

-activated by specific ‘lock and key’ recognition of foreign molecules
-driven by T and B cells
specific

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7
Q

originate in the red blood marrow and also mature in the red bone marrow

A

b cells

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8
Q

originate in the red bone marrow and also migrate to the thymus for maturation

A

t cells

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9
Q

is triggered when an antigen binds to the specific cell-surface receptors of a T or B cell

A

clonal selection

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10
Q

what are the three main pillars of immune function

A

-memory
-specificity
-self-tolerance

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11
Q

highly specific and allows rapid response to subsequent exposures

A

memory

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12
Q

the cells that recognize antigens and initiate an immune response are highly specific to one or a few similar antigens. cells which have this ability are known as immunocompetent

A

specificity

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13
Q

the immune system can distinguish our tissues (self) from foreign antigens (non-self)

A

self-tolerance

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14
Q

-humoral immunity
-red bone marrow
-plasma cells
-have memory cell formation
-plasma cells produce antibodies that inactivate antigen and tag for destruction

A

B-cells

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15
Q

-cellular immunity
-thymus
-cytotoxic T cells, helper T cells, regulatory T cells
-have cell memory formation\
-cytotoxic T cells attack infected cells and tumor cells. helper T cells activate B cells and other cells.

A

T-cells

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16
Q

a condition which the body’s immune system mistakenly attacks its own healthy tissues and organs.

A

autoimmunity

17
Q

what makes an antibody

A

produced by effector B cells called plasma cells

18
Q

a protein produced by the body’s immune system when it detects harmful substances

A

antibody

19
Q

two of the chains in a antibody monomer that are quite large and have a high molecular weight

A

heavy chains

20
Q

two chains of the antibody monomers that are only half as long and have a low molecular weight

A

light chains

21
Q

any substances that causes the body to make an immune response against that substance

A

antigen

22
Q

is the part of an antigen that binds to an antibody or antigen receptor

A

antigen determinant

23
Q

where to antibodies bind to antigens

A

the antigen-binding site, or also known as the paratope.

24
Q

what are the primary lymphoid organs/tissues

A

bone marrow and thymus
-these are sites where lymphocytes are produced and mature into functional; immune cells