lymphadenopathy

Question 1

differential for lymphadenopathy ?

Answer 1

lymphoma
infection
metastatic cancer e.g. breast/ovarian
connective tissue disease (sarcoidosis/SLE)

Question 2

symptoms of lymphoma?

Answer 2

night sweats, itch without a rash, alcohol induced pain, fatigue

Question 3

difference in lymph nodes in bacterial and viral infections ?

Answer 3

bacterial is localised and viral is generalised

Question 4

what would you expect a lymph node to feel like in lymphoma? Tender? Consistency? surface? skin inflamed?tethered?

Answer 4

non tender, rubbery/soft, smooth, no skin inflammation, no skin tethering

Question 5

if lymphoma or other malignancy is suspected - what should you ask for?

Answer 5

a surgeon to biopsy

Question 6

can a lymphoma be diagnosed on CT?

Answer 6

NO

Question 7

some lymphomas can be confirmed on histology alone, but what confirms a lymphoma and helps to classify?

Answer 7

imunochemistry

Question 8

which cells are classically seen in hodgkins lymphoma?

Answer 8

giant multinucleated cells (reed-sternberg cells) alc

Question 9

which cells are found in NHL?

Answer 9

CD20 +ve cells

Question 10

what test is very useful in leukaeias for diagnosing AML and ALL?

Answer 10

immunophenotyping