Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Respiratory System > Lung Cancer: clinical features, staging and diagnosis > Flashcards

Lung Cancer: clinical features, staging and diagnosis Flashcards

1
Q

Metastatic symptoms (4)

A

Bone pain
Spinal cord compression
Cerebral metastases
Thrombosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Paraneoplastic Symptoms (3)

A

Hyponatraemia
Anaemia
Hypercalcaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Clinical signs

A 
Chest signs
Clibbing
Lymphadenopathy
Horner's syndrome
Pancoast tumour
SVC obstruction
Hepatomegaly
Skin nodules
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is horner’s syndrome

A

a condition marked by a contracted pupil, drooping upper eyelid, and local inability to sweat on one side of the face, caused by damage to sympathetic nerves on that side of the neck.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is a pancoast tumour

A

Tumour of the pulmonary apex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Initial investigations done by GP

A 
CXR
FBC
Renal, liver functions and calcium
Clotting screen
Spirometry
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Investigations- Tissue Diagnosis

A 
Bronchoscopy
EBUS
Image guided lung/liver biopsy
FNA of neck node or skin metastases
Bone biopsy
Mediastinoscopy
Surgical excision biopsy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Treatment

A

Surgery (wedge resection, lobectomy, pneumonectomy)
Radiotherapy (radical or palliative or stereoactive)
Chemotherapy
Targeted agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are examples of target agents

A

Tyrosine kinase inhibitors and monoclonal antibodies (erlotinib, geftinib and crizotinib)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Small cell carcinoma treatment

A

Cisplatin/etoposide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Adenocarcinoma treatment

A

Cisplatin/pemetrexed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Squamous cell carcinoma treatment

A

Cisplatin/gemcitabine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

TNM

A

T: how big it is and the spread
N: Lymph node involvement
M: Metastases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What can be used to investigate T

A

CT
PET-CT
Bronchoscopy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What can be used to investigate N

A

PET-CT
Mediastinoscopy
CT
EBUS/EUS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What can be used to investigate M

A

PET-CT
CT
Bone scan

17
Q

What is the half life post injection of FDG in PET scan

A

60 minutes

18
Q

Tx/T0/Tis

A

Primary tumour can’t be assessed
No evidence of primary tumour
Carcinoma in situ

19
Q

T1

A

< or equal to 3cm in dimension

20
Q

T2

A

Tumour is between 3-5cm and involves main bronchos but not carina and invades visceral pleura

21
Q

T3

A

Tumour between 5-7cm and invades chest wall, phrenic nerve

22
Q

T4

A 
Tumour greater then 7cm and invades:
Diaphragm
Mediatinum
Heart
Great vessels
Trachea
Recurrent laryngeal nerve
Oesophagus
Vertebral body
Carina
23
Q

N0

A

No regional LN metastases

24
Q

N1

A

Ipsilateral peribronchial, hilar or intrapulmonary nodes

25
Q

N2

A

Ipsilateral mediastinal, subcarinal

26
Q

N3

A

Contralateral mediastinal, contralateral hilar, scalene, supraclavicular

27
Q

M0

A

No distant metastasis

28
Q

M1

A

Distant metastases

29
Q

PET/CT staging

A

Performs whole body staging

Respiratory System (30 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions