Lower GI Histo Flashcards
what cells of the pancreas are considered exocrine cells?
acinar cells
what do acinar cells have at the apical part that secrete stuff?
zymogen granules
when acinar cells secrete contents…what do they intially go into?
intercalated ducts
what type of cell is the one that forms the initial part of the intercalated ducts and is partially in the acinar cells?
centroacinar cells
how do centroacinar cells appear on staining?
pale cells
after going through the intercalated ducts…where do pancreatic secretions go next?
intralobular ducts and then main pancreatic ducts
what is the shape of the classic liver lobule?
a hexagon
what is at the center of the classic liver lobule?
central vein
what is at the point of each side of the hexagon on the classic liver lobule?
portal triads
what do portal triads consist of in the liver?
venule arteriole and bile duct1
what is a hepatic acinus?
two adjacent liver lobules connected
how is a hepatic acinus divided?
into three zones…123
what zone gets the most oxygen and what zone gets the least?
zone1 gets the most since it is closest to the vessels running between the lobules…zone 3 gets the least
what runs between adjacent plates of hepatocytes?
sinusoids
do sinusoids in liver have fenestration?
you betcha
what unique macrophage resides in the liver? where does it play its role?
Kupfffer cells are in the sinusoids
what lies between the sinusoid and hepatocytes?
space of disse
what cell resides in the space of disse?
ito or fat storing cells
what is the role of ito/fat storing cells?
store fat…specifically vitamin A
and make collagen if liver is compromised
what collects bile in the liver? where is it located?
bile canaliculi that are located between each hepatocyte
what type of epithelium is in the gallbladder?
simple columnar with microvilli
can the gallbladder absorb anything? if so what?
yes…absorbs water and bile
what cell is present in the epithelium of the SI?
goblet cells
what gland is present in the submucosa of the duodenum?
brunners glands
what is always within the villi that are present in the SI?
lacteals
name three types of connections between surface epithelial cells in the SI?
zonula occluden
zonula adherins
desmosomes
name the five cells types of the SI
surface epithelial cell regenerative cell goblet cells enteroendocrine cells paneth cells
what is the shape of the surface absorptive cells in the SI?
tall columnar cells with microvilli
what do surface absorptive cells have on top of them in the SI
a glycocalyx
what do goblet cells secrete?
mucinogen that turns into mucin
what do paneth cells of the SI secrete?
lysozyme
what do brunners glands of the duodenum secrete? (2)
alkaline fluid and urogastrone
what does urogastrone do to the stomach? (2)
tells it to stop acid production and make cells divide
what is the name of the plexus that innervates the muscularis externa in the SI?
Auerbachs myenteric plexus
where is the auerbachs myenteric plexus found?
between the tow layers of the muscularis externa
what is the plexus that innervates the muscularis mucoasae?
Meissners submucosal plexus
where is the meissners submucosal plexus found?
in the submucosa just beneath the muscularis mucosae
what does the appendix have that makes it different in structure from LI and SI?
has crypts of LARGE lymphoid tissue
how does the LI differ from SI in general structure?
LI does not have the Brunners glands…all else is the same
what cell does the LI not have that the SI does have?
paneth cells
name the four cell types of LI
absorptive cell
goblet cell
regenerative cell
enteroendocrine cell
