Immunology of GI

Question 1

what are two cells that help GALT tissue take up antigens?

Answer 1

M cell and dendritic cells

Question 2

what cell can directly uptake antigen in the GI tract?

Answer 2

dendritic cells

Question 3

if we are exposed to antigen orally…what can we gain from it?

Answer 3

tolerance

Question 4

what type of T cells are enlisted for immune tolerance via the GI tract?

Answer 4

Treg

Question 5

what cytokines are important for T reg cells in the GI tract?

Answer 5

IL-10 and TGFbeta

Question 6

are TGFbeta and IL10 pro or anti inflammatory?

Answer 6

anti

Question 7

what antibody is there more of in a tolerance situation?

Answer 7

IgA

Question 8

what antibody is made in the highest quantity in the GI tract?

Answer 8

IgA

Question 9

name three GI diseases you can have with IgA deficiency?

Answer 9

chronic diarrhea
ulcerative colitis
Crohns disease

Question 10

what part of the GI tract contributes most to the biome?

Answer 10

LI

Question 11

what do bacterial flagella provide for GI tract and immune system?

Answer 11

they can sorta serve as a warning and will recruit the innate immune system to act in the GI tract and prevent further infection

Question 12

what do clostridium difficile make that become problematic after antibiotic use?

Answer 12

spores that can anchor into new empty spots made by the antibiotics

Question 13

what is the main role of peyers patches?

Answer 13

coordinate immune response in the GI tract