Liver symposium Flashcards
What 5 main viruses cause viral hepatitis?
A,B,C,D,E
What 2 hepatitis viruses are enteric? Suggest how they may spread and their duration
A+E
faecal-oral, self limiting
What 3 hepatitis viruses are parenteral? Suggest how they may spread and their duration
B,C,D
blood, chronic
What is hepatitis A infection most commonly due to?
Waste management and disposal
What age is common for hep A infection and what can patients often present with?
young –> 5-14
jaundice
Who would be immunised for hepatitis A?
travellers - Africa, Asia
patients with chronic liver disease
How would you diagnose hepatitis A?
IgM antibodies
In hepatitis B what is the difference between the core antigen and E antigen?
E antigen - blood
core - liver
What does the hep B surface antigen tell us?
presence of virus - not active or inactive however
What do anti-hb antibodies tell us?
protection
What do IgM anti-HBc tell us?
acute infection
What do IgG anti-HBc tell us?
chronic infection
What do anti-HBe tell us?
inactive
What can be the 2 outcomes of chronic hep B?
no further damage
cirrhosis leading to cancer/end stage liver disease
Name 2 treatments for hepatitis B
adefovir - antiviral drugs
PEG interferon
Is hepatitis C an RNA or DNA virus?
RNA