Liver, Gallbladder, And Pancreas Flashcards
What are the lobes of the liver?
Left lobe, right lobe, caudate lobe. And caudate lobe
What does the falciform ligament do?
Separates the left and right lobes
What does the round ligament do?
Connects liver to umbilicus
What is the porta hepatis?
Where all the neviorascular structures (except hepatic veins) and hepatic ducts enter or leave
What are the arteries and veins of the liver?
Hepatic artery from celiac trunk, hepatic vein and hepatic portal vein
What type of blood is in the hepatic portal vein?
Nutrient rich, oxygen poor
What cells are found in the liver?
Hepatocyte and kupffer cells
What do hepatocytes do?
Synthesis, storage, detoxification and metabolism
What do kupffer cells do?
Phagocytosis of microbes, toxins, damaged red blood cells and white blood cells, cytokine production
Where are kupffer cells in the liver?
Hepatic sinusoids
What is a portal triad?
Bile duct, portal venue, portal arteriole
What is a hepatic lobule?
Central vein and bile canaliculi
What is gluoneogenesis?
Convert lactic acid and amino acids to glucose
What is glycogenolysis?
Glycogen breakdown into glucose
How does the liver process vitamin A?
Converted to retinal esters s useful for rods for night vision
How does the liver process vitamin D?
Utilized in bone metabolism (calcium absorption), can be synthesized
How does the liver process vitamin E?
Antioxidant (free radical scavenger)
How does the liver process vitamin k?
Utilized by hepatocytes to form functional coagulation factors
What serum proteins does the liver synthesize?
Albumin, coagulation factors, compliment factors and A and B globulins
How does the liver process drugs and hormones?
Drugs are excreted in bile, inactivated or converted into a form the kidneys can excrete
Can alter/excrete thyroid and steroid hormones
How does the liver store iron?
Ferritin
How is iron transported?
Bound to transferrin
What happens to damages red blood cells?
Return to the liver where iron is scavenged and heme is discarded as bilirubin
What happens when bilirubin accumulates?
Jaundice