Liver, Gallbladder, And Pancreas Flashcards

1
Q

What are the lobes of the liver?

A

Left lobe, right lobe, caudate lobe. And caudate lobe

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2
Q

What does the falciform ligament do?

A

Separates the left and right lobes

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3
Q

What does the round ligament do?

A

Connects liver to umbilicus

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4
Q

What is the porta hepatis?

A

Where all the neviorascular structures (except hepatic veins) and hepatic ducts enter or leave

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5
Q

What are the arteries and veins of the liver?

A

Hepatic artery from celiac trunk, hepatic vein and hepatic portal vein

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6
Q

What type of blood is in the hepatic portal vein?

A

Nutrient rich, oxygen poor

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7
Q

What cells are found in the liver?

A

Hepatocyte and kupffer cells

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8
Q

What do hepatocytes do?

A

Synthesis, storage, detoxification and metabolism

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9
Q

What do kupffer cells do?

A

Phagocytosis of microbes, toxins, damaged red blood cells and white blood cells, cytokine production

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10
Q

Where are kupffer cells in the liver?

A

Hepatic sinusoids

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11
Q

What is a portal triad?

A

Bile duct, portal venue, portal arteriole

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12
Q

What is a hepatic lobule?

A

Central vein and bile canaliculi

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13
Q

What is gluoneogenesis?

A

Convert lactic acid and amino acids to glucose

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14
Q

What is glycogenolysis?

A

Glycogen breakdown into glucose

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15
Q

How does the liver process vitamin A?

A

Converted to retinal esters s useful for rods for night vision

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16
Q

How does the liver process vitamin D?

A

Utilized in bone metabolism (calcium absorption), can be synthesized

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17
Q

How does the liver process vitamin E?

A

Antioxidant (free radical scavenger)

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18
Q

How does the liver process vitamin k?

A

Utilized by hepatocytes to form functional coagulation factors

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19
Q

What serum proteins does the liver synthesize?

A

Albumin, coagulation factors, compliment factors and A and B globulins

20
Q

How does the liver process drugs and hormones?

A

Drugs are excreted in bile, inactivated or converted into a form the kidneys can excrete
Can alter/excrete thyroid and steroid hormones

21
Q

How does the liver store iron?

22
Q

How is iron transported?

A

Bound to transferrin

23
Q

What happens to damages red blood cells?

A

Return to the liver where iron is scavenged and heme is discarded as bilirubin

24
Q

What happens when bilirubin accumulates?

25
What causes gall stones?
When cholesterol in the bile precipitates
26
What happens when the gall bladder is removed?
Expansion of the extra-hepatic bile ducts
27
What does CCK do to the gall bladder?
Causes intense contractions to release bile
28
What does secretin do?
Increase production of bicarb-rich bile by the liver hepatocytes
29
What stimulates bile production?
Parasympathetic impulses along the vagus nerve
30
What stimulates the secretion of CCK?
Fatty acid and amino acid in the chyme
31
What stimulates the release of secretin?
Acidic chyme
32
What are exocrine products and where do they go?
Pancreatic enzymes and juices enter duodenum via hepatopancreatic ampulla
33
What can gallstones lead to?
Pancreatitis
34
Where do pancreatic endocrine hormones go?
Blood stream
35
What happens during the cephalic and gastric phases?
Vagus nerve stimulation causes release of pancreatic juice
36
What happens when chyme enters the duodenum?
Causes enteroendocrine cells to release secretin and CCK
37
Where do secretin and CCK go once they're released?
To the pancreas
38
Where does insulin come from?
Beta cells of pancreatic islets
39
Where does glucagon come from?
Alpha cells of pancreatic islets
40
What is the hepatopancreatic ampulla?
Collects secretions from the gallbladder and pancreas and delivers it to the intestines
41
What is the sphincter of oddi?
Hepatopancreatic ampulla sphincter
42
What is the difference between the hepatic vein and hepatic portal vein?
Hepatic portal vein carries nutrient rich blood from the intestine, gallbladder and pancreas to the liver Hepatic vein drains the liver
43
What is bile canaliculi?
Thin tubules that receive bile secreted from the hepatocytes
44
What does the hepatic lobule do?
Diffuse oxygen and nutrients through their capillary walls -into the liver cells
45
How does the liver alter and excrete thyroid and steroid hormones?
The lives transforms and removes any excess hormone from the body