liver diseases

Question 1

liver sinusoid

Answer 1

have increased permeability, allowing larger molecules to enter and leave the bloodstream

Question 2

gall bladder

Answer 2

bigger particles from the hepatic bile ducts can go here to avoid obstruction

Question 3

bile

Answer 3

consists of bile salts, emulsifies fats

Question 4

entero-hepatic circulation

Answer 4

bile salts can be reuptaken from the colon by the hepatic portal vein

Question 5

cirrhosis

Answer 5

end-stage of fibrosis, can progress to chronic liver failure

Question 6

portal hypertension

Answer 6

formation of varices, can cause fatal bleeding

Question 7

jaundice

Answer 7

retention of bilirubin

Question 8

cholestasis

Answer 8

retention of bile in the liver

Question 9

intrahepatic cholestasis

Answer 9

reduced bile formation

Question 10

extrahepatic cholestasis

Answer 10

blockade bile secretion

Question 11

primary biliary cholangitis

Answer 11

inflammatory destruction of intrahepatic bile ducts

Question 12

primary sclerosing cholangitis

Answer 12

progressive inflammatory and sclerosing destruction of intrahepatic and extrahepatic bile ducts of all sizes

Question 13

cholelitiasis

Answer 13

gallstones in the gallbladder

Question 14

hepatitis

Answer 14

damage to hepatocytes causing inflammation

Question 15

steatosis

Answer 15

accumulation of lipids in hepatocytes

Question 16

acute liver failure

Answer 16

liver disease that is severe within 6 months

Question 17

acute on chronic failure

Answer 17

can after years suddenly develop into acute liver failure

Question 18

benign neoplasms

Answer 18

adenomas developed from hepatocytes

Question 19

malignant neoplasms

Answer 19

originating from hepatocytes or bile duct, metastatic tumour from GI tract