Hemodynamic disorders Flashcards
hyperaemia
arteriolar dilation causing increased inflow
congestion
venous contraction causing decreased outflow
extravasation of fluid
fluid goes from blood stream to lymphatic system
edema
fluid goes from the blood to the tissue
ascites
type of edema caused by low protein levels
haemorrhage
extravasation of blood from vessels
hematoma
accumulation of blood within tissue or cavities
hemostasis
natural process of blood clot formation in order to prevent or limit the extend of bleeding
thrombosis
pathological process in intact vessels
the coagulation system
one activated enzyme activates other circulating inactive enzymes
thrombin
activates platelets, helps form fibrin network, anti-coagulent effects
fibrinolysis
anti-thrombotic factor, causes fibrin degradation
PGI2
prevention of platelate adhesion to EC
endothelin
vasoconstriction
vWF and collagen
adhesion platelets
ADP and TxA2
further activation and aggregation of platelets
tissue factor
activation of thrombin
PGI2, ADO and NO
inhibit platelet aggregation
tPA
conversion of plasminogen into plasmin, causing degradation of fibrin
PAI
inhibition tPA
embolism
an intravascular obstructive mass carried by blood to a distant site
infarction
areas of ischemic necrosis
white infarct
caused by arterial occlusion
red infarct
venous outflow obstruction is less frequent
shock
impaired tissue perfusion
cardiogenic shock
heart failure
hypovolumic shock
massive blood loss
septic shock
bacterial components in circulation