diseases in the CNS Flashcards
frontal lobe
motor control, speech, smell
parietal lobe
touch, taste, body awareness
temporal lobe
hearing, facial recognition
occipital lobe
vision
cerebellum
coordination
neuronal cell body
grey matter
neuronal fibres
white matter
microglial cell
defence and immune support
astrocyte
structural and metabolic support, repair
ependymal cell
assist in production and movement of cerebral spinal fluid
oligodendrocyte
produce myelin and provide electrical insulation
hypoxia/ischemia
red neurons
neurodegenerative diseases/viral infections
intracellular inclusions, dystrophic neurites
astrocyte injury and repair
gliosis, reactive astrocytes causing hypertrophy and hyperplasia
gliosis
proliferation and hypertrophy of glial cells in response to injury
cerebral oedema
accumulation of excess fluid within the brain parenchyma
hydrocephalus
increase in fluid volume within ventricular system which increases intracranial pressure
herniation
displacement of brain tissue from one compartment to another due to increased intracranial pressure
stroke
caused by poor quality of blood vessels
meningitis
bacterial infection within the subarachnoid space, causes damage to the CNS
meningoencephalitis
infection spreads into the underlying brain
myelin
electrical insulator allowing rapid propragation of impulses
demyelinating diseases
damage to normal myelin
dysmyelinating diseases or leukodystrophy
myelin is not properly formed
multiple sclerosis
distinct episodes of neurologic deficits, caused by autoimmune response directed against myelin
relapsing-remitting MS
attack of new or worsening of syptoms, after attack they disappear
progressive-relapsing MS
symptoms will gradually become more severe, distinction between attack and remission
secondary progressive MS
symptoms will become more severe, no distinction between attack and remission
primary progressive MS
symptoms get gradually worse over time, no attacks but symptoms throughout their lives
active plaques
abundant macrophages and t cells
inactive plaques
no inflammation but no myelin, gliolisis
alzheimer disease
caused by accumulation of Tau proteins and beta-amyloid plaques
parkinson
movement disorder caused by loss of dopaminergic neurons in substantia nigra