diseases in the CNS Flashcards

1
Q

frontal lobe

A

motor control, speech, smell

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2
Q

parietal lobe

A

touch, taste, body awareness

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3
Q

temporal lobe

A

hearing, facial recognition

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4
Q

occipital lobe

A

vision

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5
Q

cerebellum

A

coordination

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6
Q

neuronal cell body

A

grey matter

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7
Q

neuronal fibres

A

white matter

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8
Q

microglial cell

A

defence and immune support

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9
Q

astrocyte

A

structural and metabolic support, repair

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10
Q

ependymal cell

A

assist in production and movement of cerebral spinal fluid

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11
Q

oligodendrocyte

A

produce myelin and provide electrical insulation

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12
Q

hypoxia/ischemia

A

red neurons

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13
Q

neurodegenerative diseases/viral infections

A

intracellular inclusions, dystrophic neurites

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14
Q

astrocyte injury and repair

A

gliosis, reactive astrocytes causing hypertrophy and hyperplasia

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15
Q

gliosis

A

proliferation and hypertrophy of glial cells in response to injury

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16
Q

cerebral oedema

A

accumulation of excess fluid within the brain parenchyma

17
Q

hydrocephalus

A

increase in fluid volume within ventricular system which increases intracranial pressure

18
Q

herniation

A

displacement of brain tissue from one compartment to another due to increased intracranial pressure

19
Q

stroke

A

caused by poor quality of blood vessels

20
Q

meningitis

A

bacterial infection within the subarachnoid space, causes damage to the CNS

21
Q

meningoencephalitis

A

infection spreads into the underlying brain

22
Q

myelin

A

electrical insulator allowing rapid propragation of impulses

23
Q

demyelinating diseases

A

damage to normal myelin

24
Q

dysmyelinating diseases or leukodystrophy

A

myelin is not properly formed

25
Q

multiple sclerosis

A

distinct episodes of neurologic deficits, caused by autoimmune response directed against myelin

26
Q

relapsing-remitting MS

A

attack of new or worsening of syptoms, after attack they disappear

27
Q

progressive-relapsing MS

A

symptoms will gradually become more severe, distinction between attack and remission

28
Q

secondary progressive MS

A

symptoms will become more severe, no distinction between attack and remission

29
Q

primary progressive MS

A

symptoms get gradually worse over time, no attacks but symptoms throughout their lives

30
Q

active plaques

A

abundant macrophages and t cells

31
Q

inactive plaques

A

no inflammation but no myelin, gliolisis

32
Q

alzheimer disease

A

caused by accumulation of Tau proteins and beta-amyloid plaques

33
Q

parkinson

A

movement disorder caused by loss of dopaminergic neurons in substantia nigra