immunology 3

Question 1

clonal expansion

Answer 1

T-cells and B-cells are monospecific so need to be cloned

Question 2

contraction

Answer 2

apoptosis of cells bound to antigens, the cells that are left form the memory

Question 3

B cell primary response

Answer 3

first exposure of naive B cell to antigen. IgM antibodies are produced

Question 4

B cell secondary response

Answer 4

memory cells can respond very fast. IgG antibodies are produced rapidly

Question 5

isotype switching

Answer 5

Helper T cells can switch what type of antigen they are producing based on the cytokine present

Question 6

Th1 response

Answer 6

stimulate phagocytosis and degradation of microbes by APC, stimulate macrophages to produce oxygen radicals, stimulate production IgG

Question 7

Th2 response

Answer 7

stimulate production of IgE, recruit eosinophils, stimulate tissue repair

Question 8

Th17 response

Answer 8

support the epithelial barrier, promotes neutrophil recruitment

Question 9

Ace2

Answer 9

helps virus get deeper into the lung