Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

GI > Liver > Flashcards

Liver Flashcards

1
Q

L1: ______: macrophages of the liver

A

Kupffer Cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

L1: Which etiology is suggested by an infiltrate of eosinophils?

A

Drug Injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

L1: Which etiology is suggested by an infiltrate of plasma cells?

A

Autoimmune hepatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

L1: Which hepatitis virus? Cannot replicate on its own

A

D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

L1: Which hepatitis virus? Contains some dsDNA

A

B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

L1: Which hepatitis virus? Never progresses to chronic liver disease

A

A, E

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

L1: Which hepatitis virus? Transmitted by fecal-oral route

A

A, E

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

L2: ______: space between hepatocyte and Kupffer cell

A

Space of Disse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

L2: _____: amount of fibrous tissue deposition

A

Stage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

L2: _____: amount of inflammation and injury

A

Grade

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

L2: Name 2 common causes of acute hepatitis

A

Acute viral hepatitis, drug injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

L2: Name the chief risk factor associated with cholangiocarcinoma.

A

Primary Sclerosing Cholangitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

L2: Name the chief risk factor associated with hepatocellular carcinoma

A

Chronic liver disease/Cirrhosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

L2: Name the mutated gene in hereditary hemochromatosis.

A

HFE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

L2: Name the mutated gene in Wilson’s Disease.

A

ATP7B (transporter in bile secretion)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

L2: Which etiology is suggested by an infiltrate of lymphocytes?

A

Viral hepatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

L2: Which etiology is suggested by an infiltrate of neutrophils?

A

Steatohepatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

L2: Which hepatitis virus? Associaed with intranasal cocaine use

A

C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

L2: Which hepatitis virus? Associated with sexual contact

A

B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

L2: Which hepatitis virus? Ground glass hepatocytes with virion inclusions in the endoplasmic reticulum

A

B

21
Q

L2: Which hepatitis virus? Higher mortality in pregnant women

A

E

22
Q

L2: Which hepatitis virus? Major cause of chronic liver disease in the US

A

B

23
Q

L2: Which hepatitis virus? Major cause of chronic liver disease worldwide

A

C

24
Q

L2: Which hepatitis virus? Progresses to chronic liver disease in 10% of patients

A

B

25
Q

L2: Which hepatitis virus? Progresses to chronic liver disease in 80% of patients

A

C

26
Q

L2: Which pathologic pattern? Anti-mitochondrial antibody in 90%; histology shows granulomatous lymphocytic cholangitis

A

Primary Biliary Cirrhosis

27
Q

L2: Which pathologic pattern? Benign mass-like proliferation of hepatocytes arising from a local vascular flow anomaly

A

Focal nodular hyperplasia

28
Q

L2: Which pathologic pattern? Benign neoplasm of hepatocytes; most common in women of childbearing age, very low risk of transformation to malignancy

A

Hepatocellular Adenoma

29
Q

L2: Which pathologic pattern? Cholangiography shows alternating strictures and dilatation of duct; no specific serologic findings

A

Primary Sclerosing Cholangitis

30
Q

L2: Which pathologic pattern? Elevated IgG and serum autoantibodies

A

Autoimmune hepatitis

31
Q

L2: Which pathologic pattern? Immune-mediated attack of small caliber bile ducts

A

Primary Biliary Cirrhosis

32
Q

L2: Which pathologic pattern? Immune-mediated obliterative fibrosis of intrahepatic and extrahepatic bile ducts

A

Primary Sclerosing Cholangitis

33
Q

L2: Which pathologic pattern? Increased de novo lipogenesis and decreased beta-oxidation

A

Alcohol-Related Steatohepatitis

34
Q

L2: Which pathologic pattern? Increased lipolysis of visceral fat due to endocrine abnormalities

A

Non-Alcohol Steatohepatitis

35
Q

L2: Which pathologic pattern? Insidious onset with pruritis appearing before jaundice, most common in middle aged women

A

Primary Biliary Cirrhosis

36
Q

L2: Which pathologic pattern? Liver disease and neuropsychiatric problems; autosomal recessive inheritance

A

Wilson’s Disease

37
Q

L2: Which pathologic pattern? Major cause of acute liver failure leading to transplant in the US

A

Acetaminophen Drug Toxicity

38
Q

L2: Which pathologic pattern? Malignant neoplasm of bile ducts

A

Cholangiocarcinoma

39
Q

L2: Which pathologic pattern? Manifests as liver disease, diabetes, and heart failure; autosomal recessive inheritance

A

Hereditary Hemochromatosis

40
Q

L2: Which pathologic pattern? Most common malignant liver tumor

A

Metastases

41
Q

L2: Which pathologic pattern? Most common primary hepatic tumor; usually small and asymptomatic

A

Hemangioma

42
Q

L2: Which pathologic pattern? Most common primary malignant liver tumor

A

Hepatocellular carcinoma

43
Q

L2: Which pathologic pattern? Neutrophilic Infiltrates and Mallory bodies

A

Alcohol-Related Steatohepatitis

44
Q

L2: Which pathologic pattern? Onion-skin periductal fibrosis with progressive disappearance of the bile duct

A

Primary Sclerosing Cholangitis

45
Q

L2: Which pathologic pattern? PiZZ genotype causing pulmonary emphysema; liver disease in 10% of patients

A

Alpha-1-Antitrypsin Deficiency

46
Q

L2: Which pathologic pattern? Steatosis and centrilobular fibrosis on histology; caused by alcohol, metabolic syndrome, or drug injury

A

Steatohepatitis

47
Q

L3: Name 3 causes of chronic hepatitis

A

Chronic viral hepatitis, autoimmune hepatitis, drug injury

48
Q

L3: Name the top 3 risk factors for Hepatitis C infection

A

IV drug abuse, multiple sexual partners, recent surgery

49
Q

L4: Name 4 patterns of fibrosis in the liver.

A

Portal fibrosis, Periportal fibrosis, Bridging fibrosis, Cirrhosis

GI (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions