lincosamides Flashcards
what is the only lincosamide called
clindamycin
contraindications with systemic use
diarrhoea states
what to do if you develop diarrhoea on clindamycin
discontinue
3 common SE with oral use - clindamycin
diarrhoea (discontinue)
abx associated colitis
abdominal pain
a general common SE of clindamycin is
skin reactions
the following occurs more frequently with clindamycin, although it can occur with most abx
abx associated colitis
important advice re Dalacin cream & conception and contraception
with vaginal use, Dalacin cream damages latex condoms and diaphragms!
important advice to give to pt who have Dalacin cream being used vaginally
it damages latex condoms and diaphragms
can clindamycin be used systemically in pregnancy
limited data
caution in 1st trimester
not known to be harmful in 2nd and 3rd trimesters
monitoring requirements with systemic use
LFTs and RFTs if treatment exceeds 10 days
the following need to be monitored if treatment exceeds 10 days
LFTs and RFTs
monitoring requirements with systemic use in children
monitor liver and renal function in neonates (0-28d) and infants
patient and carer advice
Patients and their carers should be advised to discontinue and contact a doctor immediately if severe, prolonged or bloody diarrhoea develops.
can it be used in MRSA
yes
what is Dalacin cream indicated for and what the dose?
bacterial vaginosis
1 applicatorful once daily for 3-7 nights, at night