abx prophylaxis

Question 1

rheumatic fever: prevention of recurrence. 2 options

Answer 1

phenoxymethylpenicillin or sulfadiazene

Question 2

invasive group a strep infection - prevention of secondary cases

1st line and alt

Answer 2

phenoxy
allergy: azith, or clarith or eryth (preg or within 28 days of giving birth)

Question 3

Meningococcal meningitis: prevention of secondary cases - 3 options

Answer 3

Ciprofloxacin or rifampicin or i/m ceftriaxone [unlicensed indication].

Question 4

Haemophilus influenzae type b infection: prevention of secondary disease 1st line

Answer 4

rifampicin

Question 5

diptheria - prevention of secondary cases

Answer 5

Azithromycin [unlicensed use], or clarithromycin [unlicensed use], or erythromycin (in pregnancy);

Alternative if more easily administered: benzathine benzylpenicillin [unlicensed use].

Question 6

pertussis abx prophylaxis

Answer 6

Clarithromycin (or azithromycin or erythromycin).

Question 7

Pneumococcal infection in asplenia or in patients with sickle-cell disease, antibacterial prophylaxis

Answer 7

LIFELONG
1. phenoxy
2. eryth

Antibacterial prophylaxis may be discontinued in children over 5 years of age with sickle-cell disease who have received pneumococcal immunisation and who do not have a history of severe pneumococcal infection.

Question 8

Preterm prelabour rupture of membranes (P‑PROM): prevention of intra-uterine infection

Answer 8

eryth (think - pregnancy duh)
Alternative if oral erythromycin is contra-indicated or unsuitable: consider an oral penicillin for up to 10 days or until established labour, whichever is sooner.