Limbic Association Cortex Flashcards

1
Q

True or False:

The limbic system is an integrative network of brain structures lying in the medial and inferior aspects of the brain

A

True

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2
Q

What is the oldest system in the brain

A

Limbic system

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3
Q

What are the 4 basic functional categories of the limbic system (HOME)

A
  1. Homeostasis
  2. Olfaction
  3. Memory
  4. Emotions and drives
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4
Q

What is the key structure associated with homeostasis

A

Hypothalamus

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5
Q

What is the key structure associated with olfaction

A

Olfactory cortex

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6
Q

What is the key structure associated with memory

A

Hippocampal formation

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7
Q

What is the key structure associated with emotions and drives

A

Amygdala

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8
Q

True or False:

The limbic system forms a ring on the medial aspect of the brain

A

True

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9
Q

What does the limbic system mainly consist of (2)

A
  1. Cingulate cortex

2. Parahippocampal gyri

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10
Q

How many layered hippocampal formation gyri are in the limbic system

A

3

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11
Q

What does the hippocampal formation consist of (3)

A
  1. Dentate gyrus
  2. Hippocampus proper
  3. Subiculum (in and out door)
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12
Q

Where does the hippocampal formation and the amygdala lie

A

Along the floor of the temporal horn of the lateral ventricle

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13
Q

True or False:

The amygdala and the hippocampal formation are cortical areas that are continuous with surface cortical structures

A

True

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14
Q

Where does the hippocampal formation end

A

Mamillary bodies

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15
Q

True or False:

The hippocampal formation is crucial to recent memory function

A

True

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16
Q

Where do inputs to the hippocampus come from

A

Entorhinal cortex

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17
Q

What are the 2 input pathways of the entorhinal cortex

A
  1. Perforant pathway

2. Alvear pathway

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18
Q

Where does the perforant pathway go

A

Dentate

19
Q

Where does the alvear pathway go

A

Hippocampus proper

20
Q

Which pathway is the major input pathway the perforant or alvear pathway

A

The perforant pathway

21
Q

Where do outputs from the hippocampal formation go

A

Back via the subiculum to the entorhinal cortex

22
Q

Where do outputs to anterior association cortices go

A

Through the fornix

23
Q

What is the main way out of the hippocampal formation

A

Entorhinal cortex

24
Q

What are the 2 ways out of the hippocampal formation

A
  1. Fornix

2. Entorhinal cortex

25
Q

What are the main subcortical connections of the hippocampal formation (5)

A
  1. Contralateral hippocampus
  2. Anterior nucleus of thalamus
  3. MEdidorsal nucleus of thalamus
  4. Mammillary bodies
  5. Septal nuclei
26
Q

What is lost with bilateral destruction of the hippocampus and parahippocampal gyrus

A

Profound deficit in forming new arbitrary associations and new episodic memories

27
Q

What is preserved with bilateral destruction of the hippocampus and parahippocampal gyrus (3)

A
  1. Preserved acquisition of skills (mirror reading)
  2. Preserved mirror drawing
  3. Preserved item specific priming in stem completion
28
Q

True or False:

Working memory is your present and long term memory is your past

A

True

29
Q

What do declarative episodic and semantic memory depend on

A

Medial temporal lobes

30
Q

True or False:

HM had preservation of prior knowledge and remote memories

A

True

31
Q

True or False:

HM had loss of memory for recently experienced events

A

True

32
Q

What does it mean if something is in long term memory and you can’t remember it

A

You are having a retrieval problem

33
Q

True or False:

HM had anterograde amnesia and some retrograde amnesia

A

True

34
Q

True or False:

Our episodic memories are emotional

A

True

35
Q

What type of memory did HM have deficits with

A

Declarative memory or facts and events

36
Q

True or False:

The amygdala is involved in emotion

A

True

37
Q

Where is the amygdala located

A

Just anterior to the hippocampal formation in the anterior temporal lobe

38
Q

True or False:

The amygdala is the reason we have episodic emotional memories of the past

A

True

39
Q

Does the hippocampus have a direct connection to the olfactory cortex

A

Nope

40
Q

What has a direct connection to the olfactory cortex

A

Amygdala

41
Q

True or False:

Like the hippocampal formation the amygdala has connections with association cortices and subcortical structures

A

True

42
Q

True or False:

The amygdala participates in networks mediating all major limbic system activities (HOME)

A

True

43
Q

Good luck gentlemen

A

Fuck shit up