Lichen Planus Flashcards

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1
Q

def

A

hronic inflammatory skin condition affecting skin and/or mucosal surfaces

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2
Q

what charac LP

4 p’s

A

purple polygonal pruritic papules that form plaques

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3
Q

mechh

A

T cell-mediated autoimmune disease, in which inflammatory cells attack an unknown protein within skin and mucosal keratinocytes

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4
Q

cutaneous

A

front of the wrists, lower back, and ankles

plaques often have a purple or violet hue, except on palms and soles where they are yellowish brown.

plaques are crossed by fine white lines called Wickham striae

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5
Q

cause of Wickham striae

A

stretching of skin

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6
Q

Oral lichen planus

A

inside of the cheeks sides of the tongue, gums and lips
hard palate

sign of more recalcitrant form

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7
Q

Vulval lichen planus

A

abia majora, labia minora and vaginal introitus.

Scarring, resulting in adhesions

Painful desquamative vaginitis, preventing intercourse, and causing a mucky discharge. The eroded vagina may bleed easily on contac

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8
Q

Penile lichen planus

A

classical papules in a ring around the glans

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9
Q

Lichen planopilaris

A

tiny red spiny follicular papules on the scalp

Destruction of the hair follicles leads to permanently bald patches characterised by sparse “lonely hairs”

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10
Q

Nail lichen planus

A

called twenty-nail dystrophy if all nails are abnormal and nowhere else is affected

sheding of nais

loss of nails (anonychia)

scarring of cuticle
pterygium)

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11
Q

Lichen planus pigmentosus

A

ill-defined oval, greyish brown marks on the face and neck or trunk and limbs without an inflammatory phase

provoked by sun exposure

causes dark patchy pig of lips

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12
Q

Lichen planus pigmentosus is similar to

A

Erythema dyschromicum perstans
benign skin condition characterised by well-circumscribed round to oval or irregular patches on the face, neck and trunk that are grey in colour. It is a form of acquired dermal macular hyperpigmentation.

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13
Q

Lichenoid drug eruption

A

lichen planus-like rash caused by medications.

gold

captopril

hydroxychloroquinone

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14
Q

complications

A

SCC

-enlarging nodule or an ulcer with thickened edges.

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15
Q

dg

A

clinical ft’s

patch test for mercury allergy w/ oral LP of gums

skin biopsy

  • melanin beneath dermis
  • liq degen of epidermal basal layer
  • Band of inflammatory cells just beneath the epidermis
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16
Q

rx

A

topical steroids
topical retinoids

systemic

  • oral prednisolone
  • acitrecin
  • hydroxychloroquinolone
17
Q

prog

A

perm scaring
oral 10 years
cutaneous 2 yrs