dermatitis herpetiformis Flashcards

1
Q

def

A

sub epidermal immunobullous diseases linked to celiac disease(gluten intolerance) causing a herpes like lesions

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2
Q

mech

A

gliadin fraction in gluten causes IgA to target skin and intestines

leads to inflamm seperating dermis from epidermis

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3
Q

epidem

A

caucasians
males
15-40

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4
Q

clinical features

A

symmetrical lesions
face, scalp, buttocks,
grouped vesicles extremely itchy vesicls = prurigo

resolve leaving hypo/per pig

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5
Q

dx

A

eczema

scabies

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6
Q

dg

A

skin biopsy
- granlar IgA deposish in dermal papillae

liver fun test

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7
Q

rx

A

gluten free diet prevents IgA deposits and reverses symptoms

dapsone to releive itch

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