herpes Flashcards

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1
Q

what is herpes

A

viral infection causing localised blistering

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2
Q

causative agents

A

HSV1- orofacial

HSV2-genitorectal

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3
Q

where does the herpes virus reside in latent stage

A

dorsal root spinal nerves providing cutaneous sensation

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4
Q

clinical presentation of primary type 1 infection

A

acute gingivostomatitis cervical lymphadenopathy

vesicules in lips and mucous membranes

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5
Q

how long doesprimary type 1 last `

A

2 weeks ``

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6
Q

demographic of type 1

A

children

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7
Q

clinical presentation ogf primary infection w/ hsv2

A

mx pain genital / perianal blisters

occasionaly on fingertyp in medical personel

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8
Q

presentation of reccurent herpes simplex

A

usually at same site as primary infection bbut may vary

tingling/ burning pain followed by vesicular clusters

vesicles crust in 1/2 days

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9
Q

how long does reccurent herpes last

A

12 days

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10
Q

what factors trigger reccurent episodes

A

resipiratory tract infections
UV radiation
menstruation
stress

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11
Q

dg

A

culture from vesicular fluid

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12
Q

when do antibody titres rise

A

in primary infection ONLY

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13
Q

complicationsn

A

encephalitis or meningitis w/o initial skkin signs

disseminate herpes simplex

eczema herpeticum

corneal scaring

erythema multiform

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14
Q

what is disseminated herpes simplex

A

widespread vesicules in children or immunocompromised

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15
Q

who is at risk of eczema herpeticum

A

atopic eczema patients in contact w/ herpes pts

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16
Q

how does corneal scarring occur

A

reccurent dendritic ulcers that ;ead to scarring

17
Q

rx of herpes

A

aciclovir 200 mg 5x/day 5 days
valaciclovir 1g 3x/day
7 days

18
Q

which complications require higher doeses

A

disseminated herpes simplex

eczema herpeticum

19
Q

rx to prevent reccurent episodes

A

topical penciclovir